|
NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.50B [2011] >
IJC-B Vol.50B(02) [February 2011] >
| Title: | Synthesis and antimicrobial activity of 1-(5-methyl-3-isoxazolyl)-3,6-diaryl-4-thioxo-1,3,5-triazinan-2-ones |
| Authors: | Rajanarendar, E
Raju, S
Reddy, M Nagi
Reddy, K Govardhan |
| Keywords: | Schiff bases
N-isoxazolyl- -amino isothiocyanates
Cyclization
Isoxazolyl-4-thioxo-1,3,5-triazinan-2-ones |
| Issue Date: | Feb-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Treatment of
3-benzalamino-5-methylisoxazoles 1 with
ammonium thiocyanate in hot acetic acid affords the corresponding N-isothiocyanato(phenyl)methyl-N-(5-methyl-3-isoxazolyl)amines 2a-j in excellent yields. N-Isoxazolyl-α-aminoisothiocyanates 2a-j on
reaction with aryl isocyanates undergoes cyclization to give the corresponding
isoxazolyl-4-thioxo-1,3,5-triazinan-2-ones 3a-l
in good yields. The compounds 2a-j
and 3a-l have been screened for
their antimicrobial activity. |
| Page(s): | 223-228 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.50B(02) [February 2011]
|
|
