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Title: Design and synthesis of some azole derivatives containing 2,4,5-triphenyl imidazole moiety as anti-inflammatory and antimicrobial agents
Authors: Amir, Mohd
Ahsan, Iftikhar
Akhter, Wasim
Khan, S A
Ali, Israr
Keywords: 2,4,5-Triphenyl imidazole
Issue Date: Feb-2011
Publisher: NISCAIR-CSIR, India
Abstract: A series of azole derivatives (<b style="">5a-d, 6a-d </b>and<b style=""> 7a-d</b>) have been synthesized from (2,4,5-triphenyl-imidazole-1-yl)-acetic acid hydrazide under various reaction conditions. Elemental analysis, IR, <sup>1</sup>H NMR and mass spectral data confirmed the structure of the newly synthesized compounds. All the synthesized azole derivatives have been investigated for their anti-inflammatory, antibacterial and antifungal activity and showed moderate to good activity.
Description: 207-213
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.50B(02) [February 2011]

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