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Title: Application of 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU) for the synthesis of acid azides
Authors: Naik, Shankar A
Lalithamba, H S
Sureshbabu, Vommina V
Keywords: Acid chlorides;acyl azides;peptide coupling agent;TBTU
Issue Date: Jan-2011
Publisher: NISCAIR-CSIR, India
Abstract: Conversion of acids to acyl azides using peptide coupling agent TBTU has been demonstrated. The procedure is simple and applicable to a range of carboxylic acids under mild reaction conditions. The protocol is extended to the synthesis of urethane protected amino acid azides as well.
Page(s): 103-109
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.50B(01) [January 2011]

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