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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.50B [2011] >
IJC-B Vol.50B(01) [January 2011] >
| Title: | Conventional as well as microwave assisted synthesis and antimicrobial screening of 4-aryl-3-chloro-1-[(5-nitroindazol-1-yl) acetamido]-2-oxo-azetidines |
| Authors: | Upadhyay, Apoorva
Srivastava, S K
Srivastava, S D
Yadav, R |
| Keywords: | 5-Nitroindazole
azetidinones
conventional and microwave synthesis
antimicrobial agents |
| Issue Date: | Jan-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Several
new 4-aryl-3-chloro-1-[(5-nitroindazol-1-yl) acetamido]-2-oxo-azetidines 4a-l have been synthesized from
2-(5-nitroindazol-1-yl) acetamidyl amino arylidenes 3a-l. The reactions have been carried out by both conventional as
well as microwave method. The structures of all these compounds are confirmed
by IR, 1H and 13C NMR, FAB-mass spectra and also by
microanalytical data. All the synthesized compounds have been screened for
their antibacterial activity against Escherichia
coli, Bacillus subtilis and Salmonella
typhi and antifungal activity against Aspergillus
flavus, Penicillium citrinum and Fusarium oxysporum. Some of the
synthesized compounds exhibit significant antibacterial and antifungal
activities. |
| Page(s): | 89-97 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.50B(01) [January 2011]
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