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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)] >
IJNPR Vol.1 [2010] >
IJNPR Vol.1(4) [December 2010] >
| Title: | Anti-inflammatory and antinociceptive activity of Justicia gendarussa Burm. f. leaves |
| Authors: | Shikha, P
Latha, PG
Suja, SR
Anuja, G I
Shyamal, S
Shine, VJ
Sini, S
Krishna Kumar, N M
Rajasekharan, S |
| Keywords: | Justicia gendarussa
Anti-inflammatory
Analgesic
Indomethacin
Acetyl salicylic acid |
| Issue Date: | Dec-2010 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int. cl.8—A61 K 36/00, A61P 29/00 |
| Abstract: | The ethanolic extract of Justicia gendarussa Burm.f. leaves was screened for its
anti-inflammatory and antinociceptive activity in experimental animals. The
extract showed significant inhibition of carrageenan and formalin-induced paw
oedema and cotton pellet-induced granuloma formation compared to the standard
anti-inflammatory drug, Indomethacin. The extract at 125, 250 and 500 mg/kg
showed significant inhibition of pain in the acetic acid-induced writhing and
hot plate models in mice when compared to the standard analgesic drug, acetyl
salicylic acid |
| Page(s): | 456-461 |
| CC License: |  CC Attribution- Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1033 (Online); 0379-5136 (Print) |
| Source: | IJNPR Vol.1(4) [December 2010]
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