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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
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Research Journals >
Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)] >
IJNPR Vol.1 [2010] >
IJNPR Vol.1(4) [December 2010] >
| Title: | In vitro bactericidal activity of lyophilized ethanolic extract of Indian almond (Terminalia catappa Linn.) fruit pulp on two pathogenic bacteria from subgingival plaques |
| Authors: | Rajarajan, S Asthana, Meeta Shanthi, G |
| Keywords: | Indian almond Terminalia catappa Antibiotics Oral anaerobes Subgingivitis Lyophilized extract |
| Issue Date: | Dec-2010 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int. cl.8—A61 K 36/00, A61P 31/04 |
| Abstract: | The present study is
on antibacterial activity of lyophilized ethanolic extract of unripe fresh
fruit pulp (mesocarp part) of Terminalia
catappa Linn. on two subgingival pathogenic bacteria (Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis) isolated from the outpatients reporting
to a Government-aided hospital, at Chennai,
India. These
bacteria were isolated from a pooled blood sample collected from infected
gingival, using a sterile paper point. The sample was inoculated into a test
tube containing transport media (Brain Heart Infusion Broth) and kept at 4oC.
Tryptic Soy Serum Broth (TSBV) was used to cultivate A. actinomycetemcomitans and blood agar supplemented with haemin
and vitamin was the enriched-cum-selective medium used to cultivate P. gingivalis.
Sensitivity of the isolated bacteria to standard antibiotic namely Amoxicillin,
Penicillin, Gentamycin, Norfloxacin, Metranidazole, Novobiocin, Nalidixic acid
and Vancomycin was estimated. The MIC of Seitz-filtered lyophilized ethanolic
extract for both the anaerobic bacteria was estimated as
500 µg/ml. |
| Page(s): | 466-469 |
| CC License: | CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1033 (Online); 0379-5136 (Print) |
| Source: | IJNPR Vol.1(4) [December 2010]
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