|
NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.49 [2011] >
IJEB Vol.49(01) [January 2011] >
| Title: | Antidiabetic properties of Hibiscus rosa sinensis L. leaf extract fractions on non-obese diabetic (NOD) mouse |
| Authors: | Moqbel, Fahmi S
Naik, Prakash R
Najma, Habeeb M
Selvaraj, S |
| Keywords: | Cholesterol
Glycosylated haemoglobin
H. rosa sinensi
Hyperglycemic
Insulin
VLDL |
| Issue Date: | Jan-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | On fractionation the ethanolic extract of H.
rosa sinensis leaves, 5 fractions were obtained. Of these, fraction-3 (F3)
and fraction-5 (F5) were chosen for detailed investigation on non
obese diabetic (NOD) mouse to study anti-diabetic properties because they were
more active than others. Serum glucose, glycosylated hemoglobin, triglyceride,
cholesterol, blood urea, insulin, LDL,
VLDL, and HDL were estimated. Both
fractions F3 and F5 on oral feeding (100 and 200 mg/kg body
weight) demonstrated insulinotropic nature and protective effect in NOD mice.
These fractions may contain potential oral hypoglycemic agent. |
| Page(s): | 24-29 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.49(01) [January 2011]
|
|
