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Indian Journal of Experimental Biology (IJEB) >
IJEB Vol.49 [2011] >
IJEB Vol.49(01) [January 2011] >
| Title: | Digital analysis of changes by Plasmodium vivax malaria in erythrocytes |
| Authors: | Edison, Maombi
Jeeva, J.B.
Singh, Megha |
| Keywords: | Erythrocytes
Gray level intensity
P. vivax malaria
Shape descriptors |
| Issue Date: | Jan-2011 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Blood samples of malaria patients (n =
30), selected based on the severity of parasitemia, were divided into low (LP),
medium (MP) and high (HP) parasitemia, which represent increasing levels of the
disease severity. Healthy subjects
(n = 10) without any history of
disease were selected as a control group. By processing of erythrocytes images
their contours were obtained and from these the shape parameters area,
perimeter and form factor were obtained. The gray level intensity was
determined by scanning of erythrocyte along its largest diameter. A comparison
of these with that of normal cells showed a significant change in shape
parameters. The gray level intensity decreases with the increase of severity of
the disease. The changes in shape parameters directly and gray level intensity
variation inversely are correlated with the increase in parasite density due to
the disease. |
| Page(s): | 11-15 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1009 (Online); 0019-5189 (Print) |
| Source: | IJEB Vol.49(01) [January 2011]
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