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Title: Synthesis of benzothiazole appended -lactams through [2+2]-cycloaddition reaction
Authors: Nagarajan, Arasampattu S
Kathirvelan, D
Pramesh, M
Reddy, Boreddy S R
Keywords: Benzothiazole;imine;[2+2]-cycloaddition;azetidin-2-one
Issue Date: Dec-2010
Publisher: NISCAIR-CSIR, India
Abstract: A simple and convenient protocol for the synthesis of benzo¬≠thiazole appended -lactams is described. This methodology involves [2+2]-cyloaddition of benzothiazole substituted imines with chloroacetyl chloride (CAC) in the presence of triethylamine to yield the corresponding product in moderate to good yields. The reaction is compatible with a wide variety of functional groups.
Page(s): 1662-1666
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.49B(12) December 2010]

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