|
NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(12) December 2010] >
| Title: | Quantitative structure activity relationships for the nematicidal activity of 4-amino-5-substituted aryl-3-mercapto-(4H)-1,2,4-triazoles |
| Authors: | Bijul, Lakshman A
Gupta, R L
Prasad, D |
| Keywords: | QSAR
1,2,4-triazoles
agrochemicals
nematicidal activity
Meloidogyne incognita
Rotylenchulus reniformis |
| Issue Date: | Dec-2010 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | The relationship
between the structure of a series 4-amino-5-substituted aryl-3-mercapto-(4H)-1,2,4-triazoles and their nematicidal
activity against Meloidogyne incognita
and Rotylenchulus reniformis has been
analyzed using physicochemical parameters for hydrophobic, electronic and
steric properties of the molecules by
means of multiple regression analysis. The activity of the compounds predicted
based on the QSAR models has been found comparable with the experimental
values. The QSAR study reveals that the nematicidal activity against both
nematodes is dependent on the electronic effect of ortho substituent [ F], bulkiness of para
substituent [MR (p)] and width of meta substituent [B4 (m)] of benzene ring substituents. The
higher values of these parameters are favourable for nematicidal activity. |
| Page(s): | 1657-1661 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.49B(12) December 2010]
|
|
