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Title: In vitro free radical scavenging activity of wild edible mushroom, Pleurotus squarrosulus (Mont.) Singer
Authors: Pal, Jaita
Ganguly, Sourav
Tahsin, Khandakar Saifa
Acharya, Krishnendu
Keywords: Antioxidant activity;-caroten;Chelating ability;Lycopene;NO-scavenging;Phenolics;Reducing power
Issue Date: Dec-2010
Publisher: NISCAIR-CSIR, India
Abstract: Cellular damage caused by reactive oxygen species has been implicated in several diseases and hence antioxidants have significant importance in human health. Cold water, hot water and methanolic extract of Pleurotus squarrosulus were evaluated for antioxidant activity against hydroxyl radical, DPPH (1,1-Diphenyl-2-picrylhydrazyl) radical, superoxide radical, nitric oxide (NO) scavenging, reducing power, ferrous ion chelating ability and -carotene/linoleic acid assay. Total phenol, flavonoid, -carotene and lycopene content were also determined. Hot water extract showed significant antioxidant activity in all the test systems. Hydroxyl radical scavenging activity of all the extracts has been significant compared to positive control. Hot water extract has been found to have higher phenolic, total flavonoid, -carotene and lycopene content than cold water and methanolic extract of the mushroom. Results of this study showed that, hot water extract has maximum antioxidant property and may be utilized as a promising source of therapeutics.
Page(s): 1210-1218
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Appears in Collections:IJEB Vol.48(12) [December 2010]

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