19-Jun-2013
08:41:08 IST
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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.45B [2006] >
IJC-B Vol.45B(04) [April 2006] >
| Title: | Condensed bridgehead nitrogen heterocyclic systems: Microwave assisted synthesis and bioactivity of s-triazolo[3,4- ][1,3,4]thiadiazoles, s-triazolo[3,4- ][1,3,4]thiadiazines and s-triazolo [3' ,4' :2,3]-thiadiazino[5,6- ]quinoxaline |
| Authors: | Shiradkar, Mahendra
Kale, Rajesh |
| Keywords: | Bridgehead nitrogen heterocycle
microwave synthesis
bioactivity
thiadiazole
quinoxaline |
| Issue Date: | Apr-2006 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int.Cl.7 C 0 7 D |
| Abstract: | N-[3-(4-Amino-5-mercapto-4 -[1,2,3]triazol-3-yl)-4,5,6,7-tetrahydrobenzo[ ] thiophen-2-yl]acetamide 1 on condensation
with chloroac etic acid, -haloketone and benzoin furnishes [1,2,4]triazolo[3,4- ][1,3,4]thiadiazine derivatives 2,3 and 4
respectively, while condens ation with 2,3-dichloroquinoxaline, carbon disulphide, aromatic c arboxylic ac id and aromatic
carboxaldehydes yield the cyclic products, [1,2,4] triazolo[3,4- ][1,3,4]thiadiazole derivatives 5, 6, 7,8 respectively. The
compounds have been characterized on the basis of elemental analysis and spectral data. The antibacterial, antifungal and
antitubercular activities of the compounds have also been evaluated. |
| Page(s): | 1009-1013 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.45B(04) [April 2006]
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