Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/10556
Title: Synthesis of some novel 4-substituted coumarins having potential biological activity (Part II)
Authors: Mashelkar, U C
Audi, A A
Keywords: Coumarin 4-methyl acetates
coumarin-4-methyl glyoxalate
SeO<sub>2</sub>
Issue Date: Apr-2006
Publisher: NISCAIR-CSIR, India
Series/Report no.: <b>Int Cl <sup>7</sup> C 07 D</b>
Abstract: Coumarin 4-methyl acetates are oxidized to coumarin-4-methyl glyoxalate using SeO<sub>2</sub>.Unlike the oxidative decarboxylation observed in the case of coumarin-4-acetic acid, here the oxidation is very selective for the active methylene group, without affecting the COOH group protected with ester function. The product thus obtained is analogous to the phenyl glyoxalic acid methyl ester i.e., coumarin-4-methyl glyoxalate and c an be a useful moiety for the various synthetic manipulations of heterocycles substituted at 4-position of the coumarin.
Description: 967-971
URI: http://hdl.handle.net/123456789/10556
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.45B(04) [April 2006]

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