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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.45B [2006] >
IJC-B Vol.45B(04) [April 2006] >
| Title: | Synthesis of some novel 4-substituted coumarins having potential biological activity (Part II) |
| Authors: | Mashelkar, U C
Audi, A A |
| Keywords: | Coumarin 4-methyl acetates
coumarin-4-methyl glyoxalate
SeO2 |
| Issue Date: | Apr-2006 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int Cl 7 C 07 D |
| Abstract: | Coumarin 4-methyl acetates are oxidized to coumarin-4-methyl glyoxalate using SeO2.Unlike the oxidative decarboxylation
observed in the case of coumarin-4-acetic acid, here the oxidation is very selective for the active methylene group, without
affecting the COOH group protected with ester function. The product thus obtained is analogous to the phenyl glyoxalic acid
methyl ester i.e., coumarin-4-methyl glyoxalate and c an be a useful moiety for the various synthetic manipulations of
heterocycles substituted at 4-position of the coumarin. |
| Page(s): | 967-971 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.45B(04) [April 2006]
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