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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.45B [2006] >
IJC-B Vol.45B(04) [April 2006] >
| Title: | Synthesis and biological activities ofprenylated tyrosine derivatives, themetabolites of Pithomyces ellis |
| Authors: | Venkateswarlu, Somepalli
Panchagnula, Gopala K
Subbaraju, Gottumukkala V |
| Keywords: | Prenylated tyrosine
metabolites
Pithomyces ellis
4- hydroxyphenylacetic acid
antioxidant activity
antibacterial activity |
| Issue Date: | Apr-2006 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int.Cl.7 C 07 C |
| Abstract: | 2-[4-(2E )-3-Methylbut-2-enyloxy)phenyl]ethan-1-ol
3 and 3-[4-
(2E )-3-methylbut-2-enyloxy)
phenyl]-2-(acetylamino)propanoic
Acid 8 have
been synthesized from 4-hydroxyphenylacetic acid 1 ,L-tyrosine 4 ,respectively, with an overall yield of 55% and 37%.The spectral data of synthetic 3 and 8 are in good agreement with those of natural 3 and 8, respectively These synthetic 3 and 8 show
significant brine shrimp lethality, but weak antioxidant and antibacterial ac tivities. |
| Page(s): | 1063-1066 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.45B(04) [April 2006]
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