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Title: Synthesis and antibacterial properties of some novel 2-substituted-6-(4-methyl-6-substitutedcinnoline-3-yl)imidazo[2,1-<i style="">b</i>][1,3,4]thiadiazoles
Authors: Jakhar, Anshu
Makrandi, J K
Keywords: 2-Amino-1,3,4-thiadiazoles
microwave irradiation
antibacterial properties
Issue Date: Nov-2010
Publisher: NISCAIR-CSIR, India
Abstract: A series of 2-substituted-6-(4-methyl-6-substitutedcinnoline-3-yl)imidazo[2,1-<i style="">b</i>][1,3,4] thiadiazoles <b style="">5a-k</b> have been synthe­sized by reacting 3-(2-bromoacetyl)-4-methyl-6-substitutedcin­nolines <b style="">3</b> with various 2-amino-5-substituted-1,3,4-thiadiazoles <b style="">4</b> taking absolute ethanol as solvent. The structures of the newly synthesized compounds have been characterized by elemental analysis, IR and <sup>1</sup>H NMR spectral data. All the newly synthesized compounds have been tested for their antibacterial properties against gram-positive and gram-negative bacteria.
Description: 1547-1551
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.49B(11) [November 2010]

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