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Title: Synthesis and antibacterial properties of some novel 2-substituted-6-(4-methyl-6-substitutedcinnoline-3-yl)imidazo[2,1-b][1,3,4]thiadiazoles
Authors: Jakhar, Anshu
Makrandi, J K
Keywords: 2-Amino-1,3,4-thiadiazoles;3-(2-bromoacetyl)-4-methylcinnolines;6-(cinnoline-3-yl)imidazo[2,1-b][1,3,4]thiadia¬zoles;microwave irradiation;antibacterial properties
Issue Date: Nov-2010
Publisher: NISCAIR-CSIR, India
Abstract: A series of 2-substituted-6-(4-methyl-6-substitutedcinnoline-3-yl)imidazo[2,1-b][1,3,4] thiadiazoles 5a-k have been synthe­sized by reacting 3-(2-bromoacetyl)-4-methyl-6-substitutedcin­nolines 3 with various 2-amino-5-substituted-1,3,4-thiadiazoles 4 taking absolute ethanol as solvent. The structures of the newly synthesized compounds have been characterized by elemental analysis, IR and 1H NMR spectral data. All the newly synthesized compounds have been tested for their antibacterial properties against gram-positive and gram-negative bacteria.
Page(s): 1547-1551
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.49B(11) [November 2010]

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