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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(11) [November 2010] >
| Title: | Synthesis and antibacterial properties of some novel 2-substituted-6-(4-methyl-6-substitutedcinnoline-3-yl)imidazo[2,1-b][1,3,4]thiadiazoles |
| Authors: | Jakhar, Anshu
Makrandi, J K |
| Keywords: | 2-Amino-1,3,4-thiadiazoles
3-(2-bromoacetyl)-4-methylcinnolines
6-(cinnoline-3-yl)imidazo[2,1-b][1,3,4]thiadia¬zoles
microwave irradiation
antibacterial properties |
| Issue Date: | Nov-2010 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A series of 2-substituted-6-(4-methyl-6-substitutedcinnoline-3-yl)imidazo[2,1-b][1,3,4] thiadiazoles 5a-k have been synthesized by reacting
3-(2-bromoacetyl)-4-methyl-6-substitutedcinnolines 3 with various 2-amino-5-substituted-1,3,4-thiadiazoles 4 taking absolute ethanol as solvent. The
structures of the newly synthesized compounds have been characterized by
elemental analysis, IR and 1H NMR spectral data. All the newly
synthesized compounds have been tested for their antibacterial properties
against gram-positive and gram-negative bacteria. |
| Page(s): | 1547-1551 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.49B(11) [November 2010]
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