Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/10543
Title: Synthesis of Gossypin derivatives as potential anticancer and anti-inflammatory agents
Authors: Kotra, Vijay
Ganapaty, S
Adapa, Srinivas R
Keywords: Gossypin analogues
anticancer activity
anti-inflammatory activity
Issue Date: Nov-2010
Publisher: NISCAIR-CSIR, India
Abstract: Gossypin-a potential lead from nature is isolated and a series of its derivatives (<b style="">SGGOS 1-9</b>) were synthesized and characterized by IR, <sup>1</sup>H NMR, mass spectral and elemental analyses. The <i style="">in vitro</i> cytotoxic activity on HT29 and HeLa cell lines, and <i style="">in vivo</i> anti-inflammatory activities of the compounds were evaluated. The synthesized variants have shown good anticancer and anti-inflammatory activities compared to gossypin.
Description: 1542-1546
URI: http://hdl.handle.net/123456789/10543
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.49B(11) [November 2010]

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