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NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(11) [November 2010] >
| Title: | Synthesis of Gossypin derivatives as potential anticancer and anti-inflammatory agents |
| Authors: | Kotra, Vijay
Ganapaty, S
Adapa, Srinivas R |
| Keywords: | Gossypin analogues
anticancer activity
anti-inflammatory activity |
| Issue Date: | Nov-2010 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Gossypin-a potential lead from nature is isolated and a series of its
derivatives (SGGOS 1-9) were synthesized
and characterized by IR, 1HÂ NMR, mass spectral and elemental
analyses. The in vitro cytotoxic
activity on HT29 and HeLa cell lines, and in
vivo anti-inflammatory activities of the compounds were evaluated. The
synthesized variants have shown good anticancer and anti-inflammatory
activities compared to gossypin. |
| Page(s): | 1542-1546 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.49B(11) [November 2010]
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