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IJC-B Vol.49B [2010] >
IJC-B Vol.49B(11) [November 2010] >


Title: A novel versatile strategy for synthesis of new series of 4(3H)-quinazolinone N-nucleosides
Authors: Siddiqui, I R
Singh, Pravin K
Srivastava, Vishal
Yadav, Sanjay
Singh, J
Keywords: Microwave
montmorillonite K 10
cyclisation
one-pot, quinazolinone
N-nucleoside
Issue Date: Nov-2010
Publisher: NISCAIR-CSIR, India
Abstract: An integrated protocol for one-pot synthesis of 4(3H)-quinazolinone N-nucleoside analogues under microwave irradiation by using montmorillonite K 10 as catalyst and solid support in solvent-free conditions has been reported. Results show considerable enhancement of yields and reduction in time. Integrated process minimizes the mechanical loss of the intermediate during the process of isolation. Coexistence of acidic and basic sites on surface of montmorillonite K 10 accelerates the organic reactions synergistically.
Page(s): 1535-1541
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.49B(11) [November 2010]

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