NISCAIR Online Periodicals Repository

NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR)  >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(11) [November 2010] >


Title: 2-Amino-5-sulphanyl-1,3,4-thiadiazole derivatives as anticonvulsant agents: Synthesis and evaluation [RETRACTED ARTICLE]
Authors: Pattanayak, Priyabrata
Sharma, Rajesh
Keywords: Maximal electroshock
PTZ animal model
thiadiazoles
Issue Date: Nov-2010
Publisher: NISCAIR-CSIR, India
Abstract: A series of 2-amino-5-sulphanyl-1,3,4-thiadiazole deri¬≠vatives bearing different substituents have been synthesized and screened in order to evaluate for their central nervous system activity. Anticonvulsant activity of the title compounds has been evaluated by varying the substituents in the thiadiazole moiety. The newly synthesized intermediates and compounds have been characteri¬≠zed by spectral analysis. Two of the tested compounds 3a and 3b have been found to exhibit excellent anticonvulsant activity in comparison to the reference drugs in both the pharmacological models.
Page(s): 1531-1534
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.49B(11) [November 2010]

Files in This Item:

File Description SizeFormat
IJCB 49B(11) 1531-1534.pdf79.66 kBAdobe PDFView/Open
 Current Page Visits: 764 
Recommend this item

 

National Knowledge Resources Consortium |  NISCAIR Website |  Contact us |  Feedback

Disclaimer: NISCAIR assumes no responsibility for the statements and opinions advanced by contributors. The editorial staff in its work of examining papers received for publication is helped, in an honorary capacity, by many distinguished engineers and scientists.

CC License Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India

Copyright © 2012 The Council of Scientific and Industrial Research, New Delhi. All rights reserved.

Powered by DSpace Copyright © 2002-2007 MIT and Hewlett-Packard | Compliant to OAI-PMH V 2.0

Home Page Total Visits: 511056 since 06-Feb-2009  Last updated on 11-Apr-2014Webmaster: nopr@niscair.res.in