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Journal of Scientific and Industrial Research (JSIR) >
JSIR Vol.69 [2010] >
JSIR Vol.69(11) [November 2010] >
| Title: | Performance of CFC free propellant- driven MDI of fluticasone propionate |
| Authors: | Murthy, T E G K
Priya, M Bala Vishnu
Satyanarayana, V |
| Keywords: | Emitted dose
Fluticasone propionate
Metered dose inhalers
Overages
Spray pattern
Valve delivery |
| Issue Date: | Nov-2010 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | Metered dose inhalers (MDIs)
of fluticasone propionate were developed for treatment of asthma and chronic obstructive
pulmonary disease. MDIs with hydrofluoroalkanes based propellants were
formulated with various doses, overages and various concentrations of alcohol. Optimum
requirements were found as follows: effective valve delivery, overdoses (15%); 100%
drug delivery, overages (20%); and emitted dose and fine particle fraction, alcohol
content (5-10%). |
| Page(s): | 866-871 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-1084 (Online); 0022-4456 (Print) |
| Source: | JSIR Vol.69(11) [November 2010]
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