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IJEB Vol.48(11) [November 2010] >

Title: Olfactory bulb serotonin level modulates olfactory recognition in neonate rat
Authors: Dulcy, C Prisila
Ganesh, A
Rajan, K Emmanuvel
Keywords: 5,7- Dihydroxytryptamine
Neonate rat
Olfactory recognition
Issue Date: Nov-2010
Publisher: NISCAIR-CSIR, India
Abstract: Role of serotonin in olfactory recognition was tested by depleting the olfactory bulb serotonin during postnatal day (PND)1- 4 following administration of 5,7-dihydroxytryptamine. Significant difference in the olfactory recognition test was observed during PND5-7; control pups successfully recognized and oriented towards their mother; whereas treated pups failed to recognize their mother odour. Later on, during PND12-14, both group of pups responded equally in the recognition test. Levels of olfactory bulb serotonin were depleted (53.3%) in the treated pups on PND-8, which was restored on PND-14 with only 15% variation. Further analysis demonstrated that depletion of serotonin in olfactory bulb did not affect the normal suckling and weight gain, it only modulates olfactory recognition.
Page(s): 1078-1082
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-1009 (Online); 0019-5189 (Print)
Source:IJEB Vol.48(11) [November 2010]

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