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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(10) [October 2010] >
| Title: | Microwave-assisted synthesis and antibacterial activity of 1-[3-(3-fluorophenyl) [1,8]naphthyridn-2-yl]-3-(2-oxo-2H-chromenyl)-1H-4-pyrazolecarbaldehydes using solid support |
| Authors: | Mogilaiah, K
Shiva Prasad, R
Shiva Kumar, K |
| Keywords: | Pyrazolecarbaldehydes
1,8-naphthyridine
2H-2-chromenones
Vilsmeier-Haack reagent
solid support
microwave irradiation |
| Issue Date: | Oct-2010 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | A simple and efficient
method for the synthesis of 1-[3-(3-fluorophenyl)[1,8]naphthyridn-2-yl]-3-(2-oxo-2H-chromenyl)-H-4-pyrazolecarbaldehydes
4 from
3-[2-(3-(3-fluorophenyl)[1,8]-naphthyridin-2-yl)ethanhydrazonyl]-2H-2-chromenones
(hydrazones) 3 in
the presence of DMF-POCl3 (Vilsmeier-Haack reagent) using silica gel
as solid support under microwave irradiation is described. The structural
assignments to compounds 3 and 4 are based on their elemental analyses
and spectral data. Compounds 4 have
been tested for their antibacterial activity. |
| Page(s): | 1417-1421 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.49B(10) [October 2010]
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