|
NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(10) [October 2010] >
| Title: | Synthesis and in-vitro biological evaluation of some quinazolin substituted pyrazoles, pyrazolones and 1,3,4-oxadiazoles |
| Authors: | Sah, Pramilla
Kaul, Vasudha |
| Keywords: | Quinazolin
pyrazoles
pyrazolones
1,3,4-oxadiazoles
antibacterial
insecticidal |
| Issue Date: | Oct-2010 |
| Publisher: | NISCAIR-CSIR, India |
| Abstract: | In the present study, a new series of 1′-[2-phenyl-4-oxo(3H)-quinazolin-3-(benzoyl)/2′′-methylmethine
carbonyl)]-3′,5′-dimethyl pyrazoles 6a,b,
1′-[2-phenyl-4-oxo(3H)-quinazolin-3-(benzoyl)/2′′-methylmethine
carbonyl)]-3′-methyl-5′(4H)-pyrazolones
7a,b, and [5-(3′-phenyl/methylmethine-2′-phenyl-4′-oxo(3′H)-quinazolin)-2-(4′′-chlorophenyl/3′′,5′′-dinitrophenyl/2′′-nitrophenyl)]-1,3,4-oxadiazoles
8a,b-10a,b have been synthesized
from hydrazides 5a and 5b. These compounds have been
characterized by IR, 1H NMR, mass spectra and elemental analysis.
These have been screened for their in vitro
antibacterial activity against the gram negative strains E. coli and S. aureus by
the disc diffusion technique. The insecticidal activity has been tested against
the species Callosobruchus chinensis
with legume grains as the host |
| Page(s): | 1406-1412 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.49B(10) [October 2010]
|
|
