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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
NISCAIR PUBLICATIONS >
Research Journals >
Indian Journal of Natural Products and Resources (IJNPR)
[Formerly Natural Product Radiance (NPR)] >
IJNPR Vol.1 [2010] >
IJNPR Vol.1(3) [September 2010] >
| Title: | Analysis of phytochemical variability in Neem formulations |
| Authors: | Gunasekaran, S
Anita, B |
| Keywords: | Azadirachta indica
Neem
Active principles
Limonoids
Phytochemical variability
HPLC
Quality control |
| Issue Date: | Sep-2010 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int. cl.8 - A61K 36/00 |
| Abstract: | Herbal drug development includes various steps, starting from a passport
data on raw materials, correct identification, pharmacognistic and chemical
quality, standardization, safety and randomized clinical trials. Addressing
standardization is vital and needs broader consideration. Adulteration in
market samples and availability of sub-standard products is one of the greatest
drawbacks in promotion of herbal products from India, therefore, present study was
undertaken to evaluate the phytochemical variability in neem formulations
available in the market. Five Ayurvedic formulations, containing neem as the
main ingredient was chosen for the study. The samples were tested for the
amount of limonoids like 2', 3’ dehydrosalannol, salannin, nimbolide and
azadiradione using HPLC (High-performance liquid chromatography) technique. The
wide variations in the amount of the active principles in the samples highlight
the need for stringent quality control measures in herbal industry. |
| Page(s): | 291-295 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0976-0512 (Online); 0976-0504 (Print) |
| Source: | IJNPR Vol.1(3) [September 2010]
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