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NISCAIR ONLINE PERIODICALS REPOSITORY (NOPR) >
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Research Journals >
Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)] >
IJNPR Vol.1 [2010] >
IJNPR Vol.1(3) [September 2010] >
| Title: | Antimicrobial activity of Momordica cymbalaria Fenzl aerial parts extracts |
| Authors: | Sajjan, Sangeeta Chetana, S H Paarakh, Padmaa M Vedamurthy, A B |
| Keywords: | Momordica cymbalaria Antimicrobial activity Aspergillus niger Bacteria Clinical isolate Escherichia coli Klebsiella pneumoniae Pseudomonas aeruginosa Staphylococcus aureus |
| Issue Date: | Sep-2010 |
| Publisher: | NISCAIR-CSIR, India |
| IPC Code: | Int. cl.8 - A61K 36/00, A61K 36/42, A61P 31/00, A61P 31/04, A61P 31/10 |
| Abstract: | Extracts of Momordica cymbalaria
Fenzl (Cucurbitaceae) were screened for their in vitro antimicrobial activity by agar diffusion method in
comparison with standard antibiotics, Ampicillin, Tetracycline, Streptomycin
and Gentamycin. The antimicrobial activity of petroleum ether, chloroform,
ethanol and aqueous extract of aerial parts of the plant were studied using Staphylococcus aureus, Klebsiella pneumoniae,
Escherichia coli, Pseudomonas aeruginosa (Clinical isolate, Bacteria) and Aspergillus niger (Fungi) as test organisms.
All the extracts were effective against all the four microorganisms. The result
reveals that the plant extract has very good inhibitory activity against Gram
negative organism when compared to standard antibiotics. The ethanol and
aqueous extracts of plant has shown significant activity against K. pneumoniae, E.coli,
P.aeruginosa and S. aureus.
Similarly the chloroform extract of plant has shown good inhibitory activity
against A. niger. While all standard
antibiotics had a zone of inhibition less than the extracts of M. cymbalaria indicating that the plant
can fight these organisms effectively and it could be a better alternative to
the modern medicine. |
| Page(s): | 296-300 |
| CC License: | CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0976-0512 (Online); 0976-0504 (Print) |
| Source: | IJNPR Vol.1(3) [September 2010]
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