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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(09) [September 2010] >
| Title: | Copper(II) chloride catalyzed Friedel-Crafts-type conjugate addition of indoles to , -unsaturated enones: Synthesis of 3-substituted indoles |
| Authors: | Kanwar, Deepika Rani, Rashmi Agarwal, Jyoti Peddinti, Rama Krishna |
| Keywords: | Conjugate addition copper(II) chloride indole derivatives chalcones
-indoloylketones |
| Issue Date: | Sep-2010 |
| Publisher: | CSIR |
| Abstract: | Several 3-substituted
indoles have been synthesized in good to excellent yields by conjugate addition
of indoles to , -unsaturated enones such as chalcones, methyl
vinyl ketone and cyclohexenone in the presence of catalytic amount of
copper(II) chloride. The substitution of indoles occurred exclusively at the
3-position, and products of N-alkylation
have not been observed. |
| Page(s): | 1290-1299 |
| CC License: | CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.49B(09) [September 2010]
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