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|Title:||Copper(II) chloride catalyzed Friedel-Crafts-type conjugate addition of indoles to ,-unsaturated enones: Synthesis of 3-substituted indoles|
Peddinti, Rama Krishna
|Abstract:||Several 3-substituted indoles have been synthesized in good to excellent yields by conjugate addition of indoles to ,-unsaturated enones such as chalcones, methyl vinyl ketone and cyclohexenone in the presence of catalytic amount of copper(II) chloride. The substitution of indoles occurred exclusively at the 3-position, and products of N-alkylation have not been observed.|
|Appears in Collections:||IJC-B Vol.49B(09) [September 2010]|
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