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IJC-B Vol.49B(09) [September 2010] >


Title: Copper(II) chloride catalyzed Friedel-Crafts-type conjugate addition of indoles to ,-unsaturated enones: Synthesis of 3-substituted indoles
Authors: Kanwar, Deepika
Rani, Rashmi
Agarwal, Jyoti
Peddinti, Rama Krishna
Keywords: Conjugate addition
copper(II) chloride
indole derivatives
chalcones
-indoloylketones
Issue Date: Sep-2010
Publisher: CSIR
Abstract: Several 3-substituted indoles have been synthesized in good to excellent yields by conjugate addition of indoles to ,-unsaturated enones such as chalcones, methyl vinyl ketone and cyclohexenone in the presence of catalytic amount of copper(II) chloride. The substitution of indoles occurred exclusively at the 3-position, and products of N-alkylation have not been observed.
Page(s): 1290-1299
CC License:  CC Attribution-Noncommercial-No Derivative Works 2.5 India
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.49B(09) [September 2010]

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