Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/10187
Title: A green approach to chemoselective <i style="">N</i>-acetylation of amines using catalytic amount of zinc acetate in acetic acid under microwave irradiation
Authors: Brahmachari, G
Laskar, S
Sarkar, S
Keywords: Microwave irradiation
amines
acetic acid
zinc acetate
<i style="">N</i>-acetylation
chemoselectivity
Issue Date: Sep-2010
Publisher: CSIR
Abstract: It has been found for the first time that zinc acetate alone can act as a selective <i style="">N</i>-acetylating agent without any solvent under closed vessel microwave irradiation. It is also observed that the use of a catalytic amount of this reagent in acetic acid is sufficient enough for smooth running of <i style="">N</i>-acetylation of a number of structurally diverse amines, and the reaction is chemoselective with respect to phenols, thiols, acids and alcohols. Herein is reported a simple, efficient, cost-effective and environmentally benign alternative method for chemoselective <i style="">N</i>-acetylation of amines using catalytic amount of zinc acetate in acetic acid under microwave irradiation.&nbsp; The reaction procedure requires no other solvent, and is rapid with good to excellent yields.
Description: 1274-1281
URI: http://hdl.handle.net/123456789/10187
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.49B(09) [September 2010]

Files in This Item:
File Description SizeFormat 
IJCB 49B(9) 1274-1281.pdf110.98 kBAdobe PDFView/Open


Items in NOPR are protected by copyright, with all rights reserved, unless otherwise indicated.