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Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(09) [September 2010] >
| Title: | Synthesis of some biologically important fluorinated 3-chlorochromones and 1,5-benzothiazepines as antimicrobial and antifungal agents |
| Authors: | Ghotekar, D S
Joshi, R S
Mandhane, P G
Bhagat, S S
Gill, C H |
| Keywords: | Chalcones
3-chlorochromones
1,5-benzo¬thia¬zepines
antimicrobial
antifungal agents |
| Issue Date: | Sep-2010 |
| Publisher: | CSIR |
| Abstract: | A series of synthetic
3-chlorochromones and 1,5-benzothiazepines have been synthesized and evaluated
for their antimicrobial and antifungal activity against Gram +ve and Gram -ve
microorganisms. In these series the chemical transformation of chalcones to
respective 3-chlorochromones and 1,5-benzothiazepines by using DMSO/CuCl2
and 2-aminothiophenol respectively has been carried out. Compounds
synthesized have been screened for antibacterial activity using Gentamycin and
Cefixime and for antifungal activity using Ketoconazole as reference drugs. |
| Page(s): | 1267-1270 |
| CC License: |  CC Attribution-Noncommercial-No Derivative Works 2.5 India |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.49B(09) [September 2010]
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