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Title: Synthesis and biological evaluation of some innovative coumarin derivatives containing thiazolidin-4-one ring
Authors: RamaGanesh, C K
Bodke, Yadav D
Venkatesh, K B
Keywords: Salicylaldehyde;biological agent;Schiff base;mercaptoacetic acid;thiazolidinone
Issue Date: Aug-2010
Publisher: CSIR
Abstract: The reaction of ethyl 2-oxo-2H-chromene-3-carboxylate with hydrazine followed by condensation of the resulting hydrazone with different aromatic aldehydes give the corresponding Schiff bases 5a-e. Reaction of these Schiff bases with mercaptoacetic acid furnishes the target thiazolidinone molecules 6a-e. The newly synthesized compounds have been screened for antibacterial and analgesic activities.
Page(s): 1151-1154
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.49B(08) [August 2010]

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