Please use this identifier to cite or link to this item: http://nopr.niscair.res.in/handle/123456789/10083
Title: Synthesis and anti-microbial activity of (<i style="">Z</i>)-4-(4-substituted-thiazol-2-yl)-1-(2-oxoindolin-3-ylidene) semicarbazide and its derivatives
Authors: Basavarajaiah, S M
Mruthyunjayaswamy, B H M
Keywords: Thiazole
isatin
Schiff base
anti-microbial activity
Issue Date: Aug-2010
Publisher: CSIR
Abstract: 3-[(<i>2S</i>)-3-Acetyl-5-amino-<i>N</i>-(4-substituted-thiazol-2-yl)2,3-dihydro-1,3,4-oxadiazol-2-yl]-indolin-2-yl acetates, 1-{<i>N</i>-[(<i>2R</i>)-2-(-2-oxoindolin-3-ylidene)-4-oxo-1,3-thiazolidin-3-yl]-3-(4-substituted-thiazol-2yl)ureas, <i>N</i>-(4-substituted-thiazol-2-yl)-[1,3,4]-oxadiazino[6,5]indol-3-amines and (<i>Z</i>)-4-(4-substituted-thiazol-2-yl)-1-(2-oxo-1-(substituted) methyl)indolin-3-ylidene)semicarbazides have been prepared by making use of (<i>Z</i>)-4-(4-substituted-thiazol-2-yl)-1-(2-oxoindolin-3-ylidene) semicarbazides obtained by the reaction of (4-substituted thiazole-2-yl) semicarbazides and isatin. The structures of the newly synthesized compounds have been confirmed on the basis of analytical, IR, <sup>1</sup>H NMR and mass spectral data. The newly synthesized compounds have been screened for their antimicrobial activities.
Description: 1117-1126
URI: http://hdl.handle.net/123456789/10083
ISSN: 0975-0983(Online); 0376-4699(Print)
Appears in Collections:IJC-B Vol.49B(08) [August 2010]

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