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Research Journals >
Indian Journal of Chemistry -Section B (IJC-B) >
IJC-B Vol.49B [2010] >
IJC-B Vol.49B(08) [August 2010] >
| Title: | Synthesis and anti-microbial activity of (Z)-4-(4-substituted-thiazol-2-yl)-1-(2-oxoindolin-3-ylidene) semicarbazide and its derivatives |
| Authors: | Basavarajaiah, S M
Mruthyunjayaswamy, B H M |
| Keywords: | Thiazole
isatin
Schiff base
anti-microbial activity |
| Issue Date: | Aug-2010 |
| Publisher: | CSIR |
| Abstract: | 3-[(2S)-3-Acetyl-5-amino-N-(4-substituted-thiazol-2-yl)2,3-dihydro-1,3,4-oxadiazol-2-yl]-indolin-2-yl
acetates, 1-{N-[(2R)-2-(-2-oxoindolin-3-ylidene)-4-oxo-1,3-thiazolidin-3-yl]-3-(4-substituted-thiazol-2yl)ureas,
N-(4-substituted-thiazol-2-yl)-[1,3,4]-oxadiazino[6,5]indol-3-amines and
(Z)-4-(4-substituted-thiazol-2-yl)-1-(2-oxo-1-(substituted)
methyl)indolin-3-ylidene)semicarbazides have been prepared by making use of (Z)-4-(4-substituted-thiazol-2-yl)-1-(2-oxoindolin-3-ylidene)
semicarbazides obtained by the reaction of (4-substituted thiazole-2-yl)
semicarbazides and isatin. The structures of the newly synthesized compounds
have been confirmed on the basis of analytical, IR, 1H NMR and mass
spectral data. The newly synthesized compounds have
been screened for their antimicrobial activities. |
| Page(s): | 1117-1126 |
| ISSN: | 0975-0983(Online); 0376-4699(Print) |
| Source: | IJC-B Vol.49B(08) [August 2010]
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