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IJC-B Vol.49B(08) [August 2010] >


Title: General approach to 2,4-dialkyl-3-carboxybutyrolactones: An efficient synthesis of (±)-striatisporolide A and (±)-lichesterinic acid
Authors: Patel, Ramesh M
Argade, Narshinha P
Keywords: 2-Alkylidene-3-methylsuccinimides
OsO4-dihydroxylation
dehydrative cyclizations
striatisporolide A
lichesterinic acid
synthesis
Issue Date: Aug-2010
Publisher: CSIR
Abstract: Starting from 2-alkylidene-3-methylsuccinimides, simple and efficient synthesis of the natural products striatisporolide A, lichesterinic acid and lichesterylic acid have been demonstrated via an acid catalyzed hydrolysis, esterification, OsO4-dihydroxylation and dehydrative cyclization pathway.
Page(s): 1071-1075
ISSN: 0975-0983(Online); 0376-4699(Print)
Source:IJC-B Vol.49B(08) [August 2010]

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