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Indian Journal of Geo-Marine Sciences (IJMS) >
IJMS Vol.39 [2010] >
IJMS Vol.39(2) [June 2010] >
| Title: | Antifouling sesquiterpene from the Indian soft coral, Sinularia kavarattiensis Alderslade and Prita |
| Authors: | Mol, V P Limna
Raveendran, T V
Parameswaran, P S
Kunnath, R J
Sathyan, N |
| Keywords: | Soft coral
Sinularia kavarattiensis
Sesquiterpene
Furoic acid
Balanus amphitrite |
| Issue Date: | Jun-2010 |
| Publisher: | CSIR |
| Abstract: | A sesquiterpene, (l'E,5'E)-2-(2',6'-dimethylocta-l',5',7'-trienyl)-4-furoic
acid [1], was isolated for the first time from the soft coral Sinularia kavarattiensis Alderslade
& Prita collected from Gulf of Mannar (Tamil Nadu, India). This compound
exhibited considerable larval settlement inhibition properties against the
cosmopolitan biofouler, Balanus
amphitrite. The observed mean EC50
value of 11.21 µg/ml is well within the biological potency cut off set for
natural product antifoulants (NPA’s). The low EC50 value and
favourable therapeutic ratio (5.16) coupled with its known synthetic routes
enhances the potential of 1 as a
promising NPA. |
| Page(s): | 270-273 |
| ISSN: | 0975-1033 (Online); 0379-5136 (Print) |
| Source: | IJMS Vol.39(2) [June 2010]
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