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Title: Antibacterial activity of subterranean termites used in South Indian folk medicine
Authors: Solavan A
Paulmurugan R
Wilsanand, V
Keywords: Antibacterial activity
Irular Kota tribes
Issue Date: Oct-2007
Publisher: CSIR
Series/Report no.: Int. Cl.⁸: A61K36/00, A61P11/00, A61P11/06, A61P27/00, A61P31/00
Abstract: The investigation reports antimicrobial activity of the termite species most commonly used by the South Indian tribes for treating diseases likely to be associated with microorganisms. The antibacterial activities of 90% alcohol extracts of three species of subterranean termites, viz: Microtermes obes Holmgren, Macrotermes estherae (Desneux), and Odontotermes formosanus Shiraki, their mounds and nearby soil extracts collected from three different sites of South India were assayed against various bacterial strains. The antibacterial activity was most apparent in Odontotermes formosanus Shiraki, and its mound extracts, which inhibited all the bacterial strains studied. The highest antibacterial activity was encountered in Odontotermes formosanus (12.6 ±0.5 mm) and its mound extracts (14.3 ± 1.1 mm) against E. coli BL21. The MIC values also varied with the extracts and test organisms used and ranged from 10 µg/disc to 50 µg/disc. No activity was observed in the negative control as well as soil extracts collected from near by the termite mounds. Since, the traditional knowledge of indigenous people throughout the world has played an important role in identifying natural resources worthy of commercial exploitation and the search for new pharmaceuticals from naturally occurring biological material has been guided by ethnobiological data, the results are of significance to modern medicine.
Description: 559-562
ISSN: 0972-5938
Appears in Collections:IJTK Vol.06(4) [October 2007]

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