NISCAIR Online Periodicals Repository Collection: IJC-B Vol.44B(10) [October 2005]

Bioactive compounds from the Indian ocean gorgonian Subergorgia suberosa (Pallas)

Wed, 28 Sep 2005 22:58:59 GMT

Title: Bioactive compounds from the Indian ocean gorgonian Subergorgia suberosa (Pallas)

Authors: Subrahmanyam, C; Kumar, S Ratna; Reddy, G Damodar

Abstract: From the gorgonian S. suberosa Pallas collected from the Mandapam coast, Tamil Nadu, a monohydroxy sterol mixture subergorgic acid 1, batyl alcohol 2, two pregnane derivative mixtures, thymine 3, and a new ceramide mixture in which N-hexadecanoyl-2-amino-1,3-dihydroxyoctadec-4-ene 6 is the major isomer, have been isolated. Compounds 1, 3, 6 and one of the pregnane mixtures exhibit antibacterial and antifungal activities.

Page(s): 2186-2188

Synthesis and antimicrobial screening of 2'-hydroxy-5'-(phenylazo)-N- (1", 3"-diketophenylamine)-3-chloroazetidin-2-ones

Wed, 28 Sep 2005 22:58:59 GMT

Title: Synthesis and antimicrobial screening of 2'-hydroxy-5'-(phenylazo)-N- (1", 3"-diketophenylamine)-3-chloroazetidin-2-ones

Authors: Halve, Anand K; Gour, Poonam; Dubey, Rakesh; Bhadauria, Deepti; Bhaskar, Bhuwan

Abstract: Some new 2'-hydroxy-5'-(phenylazo)-N- (1",3"-diketophenylamine)-3-chloroazetidin -2-ones 2a-l have been synthesized and their structures have been established on the basis of their elemental analysis and spectroscopic data. Compounds 2e, j and l show significant antibacterial and antifungal activity. 2'-hydroxy-5'(p-chlorophenylazo)-N-(1", 3"-diketo-p-chlorophenylamine)-3-chloroazetidin-2-one 2l has been found to be a more potent antifungal agent against A. niger and C. albicans as compared to the control drug-Fluconazole.

Page(s): 2163-2165

Synthesis of novel spiro-2-isoxazolines derived from parthenin

Wed, 28 Sep 2005 22:58:59 GMT

Title: Synthesis of novel spiro-2-isoxazolines derived from parthenin

Authors: Das, Biswanath; Ramesh, C; Ravindranath, N; Mahender, G; Holla, Harish

Abstract: Parthenin, a compound with potential anticancer and allelopathic properties, is reacted with various aldoximes in the presence of ceric ammonium nitrate to form novel spiro-2-isoxazolines.

Page(s): 2149-2151

Rapid and efficient synthesis of some biological active 2-azetidinones under microwave irradiation

Wed, 28 Sep 2005 22:58:59 GMT

Title: Rapid and efficient synthesis of some biological active 2-azetidinones under microwave irradiation

Authors: Desai, K G; Desai, K R

Abstract: An efficient and extremely fast procedure for the synthesis of 4-aryl-3-chloro-1-[(2-benzothiazolylthio)acetamidyl]-2-azetidinone 4 by the reaction of arylidene-[(2-benzothiazolylthio)acetamidyl] 3 with chloroacetylchloride in DMF in the presence of catalytic amount of triethylamine under microwave irradiation is described. A considerable increase in the reaction rate has been observed with better yield. All the compounds have been screened for their antifungal activity against Candida albicans and Aspergillus niger, and antibacterial activity against Escherchia coli, Staphylococcus aureus and Bacills substilis. In the primary screening, some of the compounds exhibit appreciable activity. The structures of the synthesised compounds 4a-j have been characterized on the basis of their elemental analysis and spectral data.

Page(s): 2093-2096

NISCAIR Online Periodicals Repository Collection: IJC-B Vol.44B(10) [October 2005]

Bioactive compounds from the Indian ocean gorgonian Subergorgia suberosa (Pallas)

Synthesis and antimicrobial screening of 2'-hydroxy-5'-(phenylazo)-N- (1", 3"-diketo­phenylamine)-3-chloroazetidin-2-ones

Synthesis of novel spiro-2-isoxazolines derived from parthenin

Rapid and efficient synthesis of some biological active 2-azetidinones under microwave irradiation

Synthesis and antimicrobial screening of 2'-hydroxy-5'-(phenylazo)-N- (1", 3"-diketophenylamine)-3-chloroazetidin-2-ones