NISCAIR Online Periodicals Repository Collection: IJC-B Vol.49B(02) [February 2010]

Ecofriendly synthesis of thieno[2,3-b]pyridines derivativies

Fri, 29 Jan 2010 22:58:59 GMT

Title: Ecofriendly synthesis of thieno[2,3-b]pyridines derivativies

Authors: Kidwai, M; Priya; Poddar, R

Abstract: In order to avoid the use of too much organic solvent and harmful catalysts, 2-aminothiophenes are readily transformed to thienopyridines by an ecofriendly synthesis in a suitable solvent system. This reaction in aqueous medium and under microwave irradiation takes lesser time and results in higher yield as compared to conventional method.

Page(s): 270-273

Synthesis of benzofuran analogs of fenamates as non steroidal antiinflammatory agents

Fri, 29 Jan 2010 22:58:59 GMT

Title: Synthesis of benzofuran analogs of fenamates as non steroidal antiinflammatory agents

Authors: Mane, Balasaheb Y; Agasimundin, Y S; Shivakumar, B

Abstract: A series of benzofuran analogs of anthranilic acid derivatives are synthesized. All the new compounds have been characterized by spectral data and elemental analyses and screened for antiinflammatory activity. Compounds 3e, 4e, 4g and 5g are found to possess antiinflammatory activity comparable to that of standard diclofenac sodium

Page(s): 264-269

A new route for the synthesis of (R)-glyceraldehyde acetonide: A key chiral building block

Fri, 29 Jan 2010 22:58:59 GMT

Title: A new route for the synthesis of (R)-glyceraldehyde acetonide: A key chiral building block

Authors: Babu, K Chandra; Ramadasu, G; Gangaiah, L; Madhusudhan, G; Mukkanti, K

Abstract: A new route for the synthesis of (R)-glyceraldehyde acetonide via asymmetric dihydroxylation of allyl 4-methoxybenzoate using the (DHQ)₂PHAL, K₂OsO₄·2H₂O catalyst system is described. This route involves the asymmetric dihydroxylation of allyl 4-methoxybenzoate, acetonide protection of vicinyl dihydroxyl groups followed by cleavage of p-methoxybenzoate ester and subsequent oxidation to give the (R)-glyceraldehyde acetonide.

Page(s): 260-263

New constituents from Psoralea corylifolia

Fri, 29 Jan 2010 22:58:59 GMT

Title: New constituents from Psoralea corylifolia

Authors: Tewari, Amit; Bhakuni, R S

Abstract: Two new metabolites, named psoralester 1 and psorachromene 2, a trans isomer of bavachromene together with five known compounds have been isolated from the seeds of Psoralea corylifolia L. and characterized on the basis of their detailed NMR and mass spectral data. Psoralester possess a ten- membered lactone moiety and a long chain ester.

Page(s): 256-259