http://nopr.niscair.res.in/handle/123456789/6040 Search the Channel search http://nopr.niscair.res.in/simple-search http://nopr.niscair.res.in/handle/123456789/6068 Title: An efficient synthesis of <img src='/image/spc_char/alpha.gif'>-(alkylidene)-5, 5-dimethyl-<img src='/image/spc_char/delta1.gif'>-lactones <br/> <br/>Authors: Parsekar, Sonia B; Amonkar, Chandan P; Nadkarni, Vishnu S; Tilve, Santosh G <br/> <br/>Abstract: 2-(-Alkylidene substituted)-5,5-dimethyl-<img src='/image/spc_char/delta1.gif'>-lactones have been synthesized in two steps. The stable phosphorane carboethoxy­methyledene (<img src='/image/spc_char/alpha.gif'>-prenyl)-triphenylphosphorane is condensed with different carbonyl compounds to afford <img src='/image/spc_char/alpha.gif'>,<img src='/image/spc_char/beta.gif'>-unsaturated esters which are cyclised using PPA to give title compounds <br/> <br/>Page(s): 1333-1336 Sat, 29 Aug 2009 22:58:59 GMT http://nopr.niscair.res.in/handle/123456789/6067 Title: A facile microwave assisted synthesis of flavones <br/> <br/>Authors: Menezes, M J; Manjrekar, S; Pai, V; Patre, R E; Tilve, S G <br/> <br/>Abstract: Chalcones <b style="">3a-f</b> on irradiation under microwave in DMSO in presence of catalytic amount of I₂ provides flavones <b style="">4a-f</b> in high yield. The corresponding chalcones <b style="">3a-f</b> are obtained by Claisen-Schimdt condensation of aromatic aldehydes with <i style="">o</i>-hydroxy acetophenone <br/> <br/>Page(s): 1311-1314 Sat, 29 Aug 2009 22:58:59 GMT http://nopr.niscair.res.in/handle/123456789/6066 Title: Enzyme catalyzed acylation of 7-hydroxy-4-methyl-2H-chromene-2-one using microwave <br/> <br/>Authors: Kidwai, Mazaahir; Mothsra, Poonam; Poddar, Roona <br/> <br/>Abstract: Acylation of pharmacologically important 7-hydroxy-4-methyl-2<i style="">H</i>-chromene-2-one has been investigated in the presence of immobilized lipase under the influence of microwave. Commercially available lipase (Novozyme 435) under microwave leads to enhancement in rate of reaction in comparison with conventional heating in immobilized lipase catalyzed acylation with various acids. Different microwave assisted technologies were studied and compared. This paper investigates the synergism between enzyme catalysis and microwaves on acylation of 7-hydroxy-4-methyl-2<i style="">H</i>-chromene-2-one, with different acids using lipase Novozyme 435 <br/> <br/>Page(s): 1307-1310 Sat, 29 Aug 2009 22:58:59 GMT http://nopr.niscair.res.in/handle/123456789/6065 Title: Simple and convenient methods for synthesis, resolution and application of aminonaphthols <br/> <br/>Authors: Periasamy, Mariappan; Anwar, Shaik; Reddy, Meda Narsi <br/> <br/>Abstract: Racemic aminonaphthols are obtained in 70-95% yield by simple and straightforward condensation of benzaldehyde, 2-naphthol and 1° or 2° amines in ethanol solvent under refluxing conditions. The racemic aminonaphthols 1-(α-aminobenzyl)-2-naphthol and 1-(α-pyrrolidinylbenzyl)-2-naphthol have been resolved using l<i>-(+)</i>-tartaric acid. The racemic 1-(α-<i>N</i>-butylaminobenzyl)-2-naphthol and 1-(α-piperidylbenzyl)-2-naphthol have been resolved using <i>R</i>-(+)-BINOL and boric acid. The racemic (2-methoxynaphth-1-yl)benzylamine is resolved using dibenzoyl-l-(-)-tartaric acid. The readiliy accessible chiral aminonaphthols are useful for resolution of important moieties like racemic BINOL, ibuprofen and mandelic acid <br/> <br/>Page(s): 1261-1273 Sat, 29 Aug 2009 22:58:59 GMT