NISCAIR Online Periodicals Repository Collection: IJC-B Vol.45B(05) [May 2006]

A facile synthesis of 2-((5R)-2-oxo-5-oxazolidinyl)methyl)-1H-isoindole-1,3(2H)-dione

Fri, 28 Apr 2006 22:58:59 GMT

Title: A facile synthesis of 2-((5R)-2-oxo-5-oxazolidinyl)methyl)-1H-isoindole-1,3(2H)-dione

Authors: Madhusudhan, G; Reddy, G Om; Ramanatham, J; Dubey, P K

Abstract: Synthesis of enantiomerically pure 2-((5R)-2-oxo-5-oxazolidinyl) methyl)-1H-isoindole-1,3(2H)-dione, a key precursor in the preparation of oxazolidinone class of antibacterial agents starting from (S)-epichlorohydrin has been achieved.

Page(s): 1264-1268

Synthesis of novel unsaturated purine nucleoside

Fri, 28 Apr 2006 22:58:59 GMT

Title: Synthesis of novel unsaturated purine nucleoside

Authors: Singh, Virendra

Abstract: 5′-Silylated derivative of N⁶-n-propyladenosine 1 has been converted to bisxanthate 2 by reaction with CS₂followed by alkylation.The bisxanthate affords 2′, 3′-didehydro-2′, 3′-dideoxy-N⁶-n-propyladenosine 4 on reduction with tri-n-butyltin hydride and desilylation.

Page(s): 1325-1327

Synthesis of S-hepta-O-acetyl lactosyl-1,5-disubstituted-2-isothiobiurets and 1,5-disubstituted-2,4-isodithiobiurets

Fri, 28 Apr 2006 22:58:59 GMT

Title: Synthesis of S-hepta-O-acetyl lactosyl-1,5-disubstituted-2-isothiobiurets and 1,5-disubstituted-2,4-isodithiobiurets

Authors: Mangte, D V; Deshmukh, S P

Abstract: Several S-hepta-O-acetyl lactosyl-1,5-disubstituted-2-isothiobiurets 4 and 1,5-disubstituted-2,4-isodithiobiurets 5 have been synthesized by the interaction of S-hepta-O-acetyl lactosyl-1-arylisothiocarbamides 3 with phenyl isocyanate and phenyl isothiocyanate, respectively. The identities of these newly synthesized compounds are established on the basis of elemental analysis, IR, NMR and mass spectral analysis.

Page(s): 1285-1287

Synthesis of some novel 5, 6-dihydro-6-[4'-substituted phenyl]-12H- indeno [2, 1-c]-1, 5-benzodiazepin-7-ones

Fri, 28 Apr 2006 22:58:59 GMT

Title: Synthesis of some novel 5, 6-dihydro-6-[4'-substituted phenyl]-12H- indeno [2, 1-c]-1, 5-benzodiazepin-7-ones

Authors: Aggarwal, Preeti; Kamboj, Ramesh C; Gupta, Satish C; Dhawan, Som N

Abstract: Synthesis of hitherto unknown 5, 6-dihydro-6-phenyl-12H-indeno[2, 1-c]-1, 5-benzodiazepin-7-ones 2 through Michael type addition of o-phenylenediamine to 2-benzylideneindane-1, 3-diones is reported.

Page(s): 1322-1324