http://nopr.niscair.res.in/handle/123456789/5167 Search the Channel search http://nopr.niscair.res.in/simple-search http://nopr.niscair.res.in/handle/123456789/5686 Title: Hepatoprotective and antioxidant activities of flowers of <i style="">Calotropis procera</i> (Ait) R. Br. in CCl₄ induced hepatic damage <br/> <br/>Authors: Qureshi, Absar Ahmed; Prakash, T; Patil, Tushar; Swamy, A H M Viswanath; Gouda, A Veeran <br/> <br/>Abstract: Hepatoprotective activity of 70% ethanolic extract of flowers of <i style="">C. procera</i> was studied against CCl₄ induced hepatic injury in albino rats and mice. In addition, antioxidant activity was studied by <i style="">in vitro</i> models. Pre-treatment with 70% ethanolic extract (CPA) reduced the biochemical markers of hepatic injury like serum glutamate pyruvate transaminase, serum glutamate oxaloacetate transaminase, alkaline phosphatase, bilirubin, cholesterol, HDL and tissue glutathione (GSH) levels. Similarly pretreatment with CPA reduced the CCl₄ induced elevation in the pentobarbitone sleeping time. Histopathological observations also revealed that pretreatment with CPA protected the animals from CCl₄ induced liver damage. CPA demonstrated dose dependant reduction in the <i style="">in vitro</i> and <i style="">in vivo</i> lipid peroxidation induced by CCl₄. In addition it showed dose dependant free radical scavenging activity. The results indicate that flowers of <i style="">C. procera</i> possess hepatoprotective property possibly because of its anti-oxidant activity. This property may be attributed to the quercetin related flavonoids present in the flowers of <i style="">Calotropis procera</i>. <br/> <br/>Page(s): 304-310 Mon, 26 Feb 2007 22:58:59 GMT http://nopr.niscair.res.in/handle/123456789/5683 Title: Rapid micropropagation via axillary bud proliferation of <i style="">Adhatoda vasica</i> Nees from nodal segments <br/> <br/>Authors: Abhyankar, Gauri; Reddy, V D <br/> <br/>Abstract: A protocol for rapid multiplication of <i style="">Adhatoda vasica</i> has been developed through nodal explants from field grown mature plants. The maximum number of shoots, i.e., 7.75 <u>+</u> 0.392 differentiated from split nodal halves on MS medium supplemented with BA (10.0 mg/l) during 4 weeks of culture. Maximum number of shoots formed per explant increased to ca. 30 within 6 weeks of subculture on medium containing BA (1.0 mg/l) and Kn (1.0 mg/l). The isolated shoots rooted 90% in MS medium containing IBA (0.1 mg/l) in 2 weeks. The rooted plantlets were successfully transferred to soil in glasshouse and subsequently in field. The plantlets rooted in liquid medium did not survive, but those rooted on solid medium showed more than 75% survival. <i style="">In vitro</i> raised plants grew successfully <i style="">ex vitro </i>till flowering. <br/> <br/>Page(s): 268-271 Mon, 26 Feb 2007 22:58:59 GMT http://nopr.niscair.res.in/handle/123456789/5682 Title: Effect of GnRH on guinea pig endometrium at preimplantation stage <br/> <br/>Authors: Jelodar, G A; Gholami, S; Jafarpour, F <br/> <br/>Abstract: Endometrium of GnRH treated group resembled with pregnant group and endometrial thickness in these groups significantly increased in comparison with non-pregnant group. In GnRH treated animals, most of histomorphological changes in epithelial cells, glands and stroma of uterus was similar to pregnant group. The results revealed that mammalian form of GnRH exerted endometrial change in guinea pig almost similar to those occur in normal pregnant animals and its administration prior to implantation may improve pregnancy rate following embryo transfer. <br/> <br/>Page(s): 242-246 Mon, 26 Feb 2007 22:58:59 GMT http://nopr.niscair.res.in/handle/123456789/5252 Title: Preventive role of <i style="">Gynandropsis gynandra</i> L., against aflatoxin B₁ induced lipid peroxidation and antioxidant defense mechanism in rat <br/> <br/>Authors: Sivanesan, D; Begum, V Hazeena <br/> <br/>Abstract: <i style="">G.gynandra</i> extract was found to potentially diminish the rate of lipid peroxidation, with a significant increase in the levels of enzymatic (superoxide dismutase, catalase and glutathione peroxidase) and non-enzymatic (reduced glutathione vitamins E and C, and uric acid) antioxidants, which were found, altered during aflatoxin B₁ (AFB₁) injection. The result confirmed that <i style="">G.gynandra</i> extract exerts its chemopreventive efficacy by preventing the rate of lipid peroxidation and influenced the enzymatic and non-enzymatic antioxidants in AFB₁ induced male albino rats. <br/> <br/>Page(s): 299-303 Mon, 26 Feb 2007 22:58:59 GMT