NISCAIR Online Periodicals Repository Collection: JSIR Vol.65(06) [June 2006]

Analytical techniques used to characterize drug-polyvinylpyrrolidone systems in solid and liquid states – An overview

Mon, 29 May 2006 22:58:59 GMT

Title: Analytical techniques used to characterize drug-polyvinylpyrrolidone systems in solid and liquid states – An overview

Authors: Chadha, Renu; Kapoor, V K; Kumar, Amit

Abstract: Homogeneous distribution of poorly water-soluble drugs in polyvinylpyrrolidone (PVP), a hydrophilic carrier, is definitely a suitable way to improve the bioavailability of such drugs. However, fundamental knowledge of drug polymer interaction and comprehensive study of the thermal, structural and solubility properties of such binary systems is the prerequisite for the development of useful drug product. The paper reviews physical state, dissolution behavior and elucidation of drug-PVP interaction in solid dispersion using XRD, FTIR, DSC, SEM, hot stage microscopy and NMR. The importance of suitable selection of the system preparation methods have also been demonstrated and emphasis is laid on the potential methods for the industrial production of solid dispersions.

Page(s): 459-469

Kinetics and mechanism of polymerization of vinyl acetate using triphenyl stibonium 1, 2, 3, 4-tetraphenyl- cyclopentadiene ylide

Mon, 29 May 2006 22:58:59 GMT

Title: Kinetics and mechanism of polymerization of vinyl acetate using triphenyl stibonium 1, 2, 3, 4-tetraphenyl- cyclopentadiene ylide

Authors: Srivastava, A K; Chaurasia, A K; Sharma, Saroj; Mishra, Garima

Abstract: This study describes the kinetics and mechanism of free radical polymerization of vinyl acetate initiated by triphenyl stibonium 1,2,3,4-tetraphenylcyclopentadiene ylide in dioxane at 75±0.1°C under nitrogen atmosphere. The system followed ideal radical kinetics (R_p [M] [I]^0.5). The reaction has been retarded by hydroquinone, aniline and nitrobenzene. The overall activation energy and average value of k_p²/k_t are 32 kJ mol^-1 and 0.46 l mol^-1s^-1, respectively.

Page(s): 514-517

Development of four channel programmable FES system using multi-tap transformers

Mon, 29 May 2006 22:58:59 GMT

Title: Development of four channel programmable FES system using multi-tap transformers

Authors: Sharma, V K; Agnihotri, R C; Pankaj, Dinesh; Kumar, Neelesh; Jindal, Rohit; Mehta, Deepak; Bahadur, Raj

Abstract: Spinal cord injuries are predominantly prevalent among younger individuals (> 55% in 16-30 age group). Functional electrical stimulation (FES) is electrical stimulation of muscle deprived of nerves control, with a view of providing muscular contraction and providing a functionally useful movement. The paper reports on the development of a FES system using multi-tap transformers, and also usefulness of the system on a complete paraplegic patient with injury level T-4 to T-12.

Page(s): 507-509

An implementation and usability evaluation of automatic cash-payment system for hospital

Mon, 29 May 2006 22:58:59 GMT

Title: An implementation and usability evaluation of automatic cash-payment system for hospital

Authors: Yang, Hui-Jen; Lay, Yun-Long; Tsai, Chung-Ho

Abstract: Most hospitals have the information system to deal with the register, billing and payment process in Taiwan. The payment mechanism is mainly by cash that is counted by the counter clerks. In order to lessen the workload of counter clerks and reduce the patient’s waiting time for speeding up the payment process, this study thus implemented a hospital automatic cash-payment (HACP) system. An experimental evaluation was also conducted to survey the perceptions of patient’s feeling about the system. The results displayed that relative advantage of system, complexity of system and perceived service quality of system have significantly effected on behavioral intention of HACP system use. Perceived service quality has most predictive power to the behavioral intention of system use. Behavioral intention of HACP system use has in turn positively effected on actual system use of HACP system.

Page(s): 485-494