http://nopr.niscair.res.in/handle/123456789/312 Search the Channel search http://nopr.niscair.res.in/simple-search http://nopr.niscair.res.in/handle/123456789/483 Title: Synthesis and characterization of new quinazolines as potential antimicrobial agents <br/> <br/>Authors: Desai, N C; Shihora, P N; Moradia, D L <br/> <br/>Abstract: Ethyl 4-[2-(2-chlorophenyl)-4-oxo-3-hydroquinazolin-3yl]benzoate 1 which reacts with hydrazine hydrate in presence of methanol resulted into N-amino{4-[2-(2-chlorophenyl)-4-oxo(3-hydroquinazolin-3-yl)phenyl}carboxamide 2. Compound 2 on treatment with aryl isothiocyanates in presence of acetone is converted into aryl-N-{[({4-[2- (2-chlorophenyl)-4-oxo(3-hydroquinazolin-3-yl)]phenyl}carbonylamino)amino]thioxo methyl}amides 3. Compound 3, in presence of sulphuric acid has yielded aryl-N-(5-{4-[2-(2-chlorophenyl)-4-oxo(3-hydroquinazolin-3-yl)]phenyl}(1,3,4,thiadiazol-2-yl))amides 4a-l. Newly synthesized compounds 4a-l have been screened for their antibacterial and antifungal activities on Eschericia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Staphylococcus pyogenes, C. albicans, A. niger and A. clavatus. <br/> <br/>Page(s): 550-553 Mon, 26 Feb 2007 22:58:59 GMT http://nopr.niscair.res.in/handle/123456789/482 Title: Synthesis and bioactivity study of 2,5-bismercapto-1,3,4- thiadiazole heterocyclic derivatives <br/> <br/>Authors: Li, Man-Lin; Zhang, You-Ming; Wei, Tai-Bao <br/> <br/>Abstract: A series of acylhydrazone compounds 3a-i and acylthiosemicarbazides 4a-h containing thiadiazole rings have been synthesized conveniently in high yields. Some heterocyclic derivatives 5 are prepared by the method of dehydration of compounds 4. Structure of all these compounds have been confirmed by elemental analysis, IR, ¹H and ¹³C NMR. The bioassay result indicates that some compounds have relatively low antibacterial activity and other compounds have bioactivity for improving plant growth. <br/> <br/>Page(s): 544-549 Mon, 26 Feb 2007 22:58:59 GMT http://nopr.niscair.res.in/handle/123456789/477 Title: Reaction of 2-acetyl benzofuranhydrazone with aromatic aldehydes: Formation of aldzaines and regeneration of 2-acetylbenzofuran <br/> <br/>Authors: Ujjinamatada, Ravi K; Agasimundin, Yankanagouda S <br/> <br/>Abstract: Hydrolytic cleavage of 2-acetylbenzofuranhydrazone under acidic condition with aromatic aldehyde is described. This method of cleavage of C=N bond is shown to serve as a convenient method for the regeneration of ketone from ketohydrazone besides synthesis of aldazines. <br/> <br/>Page(s): 540-543 Mon, 26 Feb 2007 22:58:59 GMT http://nopr.niscair.res.in/handle/123456789/473 Title: Enamination of 1,3-dicarbonyl compounds catalyzed by tin tetrachloride <br/> <br/>Authors: Zhang, Zhan-Hui; Ma, Zi-Chuan; Mo, Li-Ping <br/> <br/>Abstract: Tin tetrachloride has been found to be an extremely efficient catalyst for the enamination of 1,3-dicarbonyl compounds under solvent-free conditions at room temperature. <br/> <br/>Page(s): 535-539 Mon, 26 Feb 2007 22:58:59 GMT