http://nopr.niscair.res.in/handle/123456789/11686 Search the Channel search http://nopr.niscair.res.in/simple-search http://nopr.niscair.res.in/handle/123456789/11696 Title: An efficient one-pot synthesis of isoxazolyl polyhydroquinolines <i style="">via</i> Hantzsch condensation using L-proline as catalyst <br/> <br/>Authors: Rajanarendar, E; Reddy, M Nagi; Raju, S <br/> <br/>Abstract: L-Proline is employed as an efficient organo catalyst for the one-pot, four component Hantzsch reaction for the synthesis of isoxazolyl polyhydroquinoline derivatives. This method is environmentally benign, affords excellent yields and has operational simplicity and isoxazole amines are used for the first time in this synthesis. <br/> <br/>Page(s): 751-755 Thu, 28 Apr 2011 22:58:59 GMT http://nopr.niscair.res.in/handle/123456789/11695 Title: An efficient Friedlander condensation using Zr(OH)₂CO₃.ZrO₂ as catalyst in the solid stat <br/> <br/>Authors: Mogilaiah, K; Swamy, T Kumara; Chandra, A Vinay <br/> <br/>Abstract: A simple and efficient Friedlander condensation of 2-amino-nicotinaldehyde <b>1 </b>with various carbonyl compounds containing <img src='/image/spc_char/alpha.gif' border=0>-methylene group <b>2</b> under solid state conditions to prepare 1,8-naphthyridines <b>3 </b>in very good yields using<b> </b>Zr(OH)₂CO₃.ZrO₂as catalyst has been described. <br/> <br/>Page(s): 748-750 Thu, 28 Apr 2011 22:58:59 GMT http://nopr.niscair.res.in/handle/123456789/11694 Title: Microwave assisted one-pot synthesis of nitrogen and oxygen containing heterocycles from acyl Meldrum’s acid <br/> <br/>Authors: More, D H; Mahulikar, P P <br/> <br/>Abstract: One-pot syntheses of biologically active nitrogen and oxygen containing heterocyclic compounds such as uracils and thiouracils<b style=""> </b>and 1,4-benzothiazines, 4-methylcoumarins and 4<i>H</i>-1,4-dihydropyridines, using acyl Meldrum’s acids are reported. <br/> <br/>Page(s): 745-747 Thu, 28 Apr 2011 22:58:59 GMT http://nopr.niscair.res.in/handle/123456789/11693 Title: Synthesis of oxadiazoles and pyrazolones as a antimycobacterial and antimicrobial agents <br/> <br/>Authors: Thaker, K M; Ghetiya, R M; Tala, S D; Dodiya, B L; Joshi, K A; Dubal, K L; Joshi, H S <br/> <br/>Abstract: Heterosubstituted oxadiazoles and pyrazolones derivatives have been synthesized by reaction of 3,5-dichlorobenzo[<i style="">b</i>]­thiophene-2-carbohydrazide <b style="">1</b> and arylaldehydes in dioxane to afford (<i style="">E</i>)-<i>N</i>’-Arylmethylidene-3,5-dichlorobenzo[<i style="">b</i>]thiophene-2-carbohydrazides <b style="">2a-k</b>. Compounds <b style="">2a-k</b> on reaction with acetic anhydride give 5-(3,5-dichlorobenzo[<i style="">b</i>]thiophen-2-yl)-2-aryl-3-acetyl-(2<i style="">H</i>)1,3,4-oxadiazoles <b style="">3a-k</b>. Furthermore, compound <b style="">1</b> on reaction with Ethyl (2<i>E</i>)-3-oxo-2-arylhydrazinylidene butanoate in presence of glacial acetic acid gives (4<i>E</i>)-2-[(3,5-dichloro­benzo[<i style="">b</i>]thiophen-2-yl)carbonyl]-5-methyl-4-arylhydrazinylidene-2,4-dihydro-3<i>H</i>-pyrazolone <b style="">4a-k</b>.<b style=""> </b>Their IR, ¹H NMR, mass spectral data<b style=""> </b>and elemental analysis are in accord with assigned structure. All the newly synthesized compounds have been screened for their antimicrobial activity and antitubercular activity. <br/> <br/>Page(s): 738-744 Thu, 28 Apr 2011 22:58:59 GMT