http://nopr.niscair.res.in/handle/123456789/7524 Search the Channel search http://nopr.niscair.res.in/simple-search http://nopr.niscair.res.in/handle/123456789/7544 Title: Improved synthesis of chalcones and pyrazolines under ultrasonic irradiation <br/> <br/>Authors: Gupta, Ragini; Gupta, Neetu; Jain, Anshu <br/> <br/>Abstract: <smarttagtype namespaceuri="urn:schemas-microsoft-com:office:smarttags" name="country-region"><smarttagtype namespaceuri="urn:schemas-microsoft-com:office:smarttags" name="place"> Five 1,3-diarylprop-2-en-1-ones <b style="">3a-e</b> are synthesized by Claisen-Schmidt condensation of aryl methyl ketones and 4-chlorobenzaldehyde to give pyrazolines <b style="">5a-e</b> by cyclization with phenylhydrazine in gl. acetic acid using ultrasonic irradiation in lesser time with higher yields. All the synthesized compounds are characterized by elemental analyses and spectral data IR, PMR and are screened for their antimicrobial activities. Some of them have shown promising results against <i style="">E. coli</i>, <i style="">S. aureus, C. albicans </i>and <i style="">A. niger. </i> </smarttagtype></smarttagtype> <br/> <br/>Page(s): 351-355 http://nopr.niscair.res.in/handle/123456789/7543 Title: Microwave-enhanced Knoevenagel condensation catalysed by NH₂SO₃NH₄ <br/> <br/>Authors: Mogilaiah, K; Babu, H Sharath; Vidya, K; Kumar, K Shiva <br/> <br/>Abstract: Ammonium sulphamate catalyses the efficient Knoevenagel condensation of aromatic aldehydes <b style="">1 </b>with active methylene compounds in solvent-free conditions under microwave irradiation to give arylidene derivatives <b style="">3. </b>The yields are excellent and purity is high. The method is preoperatively convenient and useful. <br/> <br/>Page(s): 390-393 http://nopr.niscair.res.in/handle/123456789/7542 Title: Claisen-Schmidt condensation under solvent-free conditions <br/> <br/>Authors: Mogilaiah, K; Swamy, T Kumara; Chandra, A Vinay; Srivani, N; Vidya, K <br/> <br/>Abstract: Claisen-Schmidt condensation of 2-(4-acetyl-phenylamino)-3-(4-chlorophenyl)-1,8-naphthyridine 3 with various aromatic aldehydes under solvent-free conditions to prepare α-β-unsaturated ketones 4 using solid NaOH as catalyst has been described. The reaction proceeds efficiently at room temperature in high yields and in a state of excellent purity. <br/> <br/>Page(s): 382-385 http://nopr.niscair.res.in/handle/123456789/7541 Title: Synthesis of bis(arylamino)thiazoloylindoles as novel analogs of dendrodoine <br/> <br/>Authors: Reji, T F Abbs Fen; Manju, S L; Rajasekharan, K N <br/> <br/>Abstract: 3-[2,4-Bis(arylamino)thiazol-5-oyl]indoles, as the analogs of the cytotoxic marine alkaloid dendrodoine, are synthesized from 1-(<i>N</i>,<i>N</i>'-diarylamidino)-3-arylthioureas which provided the four [S1-C2-N3-C4] ring atoms for the thiazole ring construction. The remaining carbon of the thiazole is sourced from 3-(2-bromoacetyl)indole. This [4+1] heterocyclization reaction provided novel 3-[2,4-bis(arylamino)thiazol-5-oyl]indoles, which are characterized by elemental analysis, IR, NMR and FAB Mass spectral data and showed moderate antibacterial activity. <br/> <br/>Page(s): 323-326