http://nopr.niscair.res.in/handle/123456789/5171 Search the Channel search http://nopr.niscair.res.in/simple-search http://nopr.niscair.res.in/handle/123456789/5530 Title: Reversal of hepatotoxin-induced pre-fibrogenic events by <i style="">Emblica officinalis</i> – A histological study <br/> <br/>Authors: Mir, A I; Kumar, B; Tasduq, SA; Gupta, D K; Bhardwaj, S; Johri, R K <br/> <br/>Abstract: Efficacy of a herbal product of <i style="">E. officinalis </i>(fruit)<i style=""> </i>(EO) has been evaluated against carbon tetrachloride (CCl₄)and thioacetamide (TAA) induced changes in rat liver. Chronic treatment of CCl₄ and TAA revealed abnormal histopathology indicative of pre-fibrogenic events. EO reversed such alterations with significant regenerative changes suggestive of its preventive role in prefibrogenesis of liver. <br/> <br/>Page(s): 626-629 http://nopr.niscair.res.in/handle/123456789/5341 Title: Biosorption of Cr (VI) with <i style="">Trichoderma viride</i> immobilized fungal biomass and cell free Ca-alginate beads <br/> <br/>Authors: Bishnoi, Narsi R; Kumar, Rajender; Bishnoi, Kiran <br/> <br/>Abstract: Ability of Cr (VI) biosorption with immobilized <i style="">Trichoderma viride</i> biomass and cell free Ca-alginate beads was studied in the present study. Biosorption efficiency in the powdered fungal biomass entrapped in polymeric matric of calcium alginate compared with cell free calcium alginate beads. Effect of <i style="">p</i>H, initial metal ion concentration, time and biomass dose on the Cr (VI) removal by immobilized and cell free Ca-alginate beads were also determined. Biosorption of Cr (VI) was <i style="">p</i>H dependent and the maximum adsorption was observed at <i style="">p</i>H 2.0. The adsorption equilibrium was reached in 90 min. The maximum adsorption capacity of 16.075 mgg^-1was observed at dose 0.2 mg in 100 ml of Cr (VI) solution. The high value of kinetics rate constant K_ad(3.73×10^-2) with immobilized fungal biomass and (3.75×10^-2) with cell free Ca-alginate beads showed that the sorption of Cr (VI) ions on immobilized biomass and cell free Ca-alginate beads followed pseudo first order kinetics. The experimental results were fitted satisfactory to the Langmuir and Freundlich isotherm models. The hydroxyl (-OH) and amino (-NH) functional groups were responsible in biosorption of Cr (VI) with fungal biomass spp. <i style="">Trichoderma viride</i> analysed using Fourier Transform Infrared (FTIR) Spectrometer. <br/> <br/>Page(s): 657-664 http://nopr.niscair.res.in/handle/123456789/5340 Title: Involvement of p38 MAPkinase in attenuation of antinociceptive effect of morphine in diabetic mice <br/> <br/>Authors: Gilhotra, Neeraj; Sharma, Ajay; Singh, Manjeet; Dhingra, Dinesh <br/> <br/>Abstract: Experimental diabetes induced by streptozotocin (200 mg/kg, ip) markedly decreased the antinociceptive effect of morphine and significantly increased the urinary nitrite concentration. Administration of FR-167653 (a selective p38MAPKinase inhibitor) in a dose of 4 mg/kg improved the antinociceptive effect of morphine and attenuated the increase in urinary nitrite concentration in diabetic mice. It may be concluded that diabetes-induced decrease in antinociceptive effect of morphine may be due to induction of p38 MAPKinase activity. <br/> <br/>Page(s): 654-656 http://nopr.niscair.res.in/handle/123456789/5339 Title: An enzyme-linked immunosorbent assay (ELISA) to measure growth hormone level in serum and milk of buffaloes (<i style="">Bubalus bubalis)</i> <br/> <br/>Authors: Mishra, A; Goswami, T K; Shukla, D C <br/> <br/>Abstract: An indirect Sandwich ELISA to measure growth hormone level in serum and milk of buffaloes was developed. The assay was based on purified anti rbST IgG raised in rabbits and chicken and rabbit anti chicken IgG horseradish peroxidase. The assay was validated in terms of sensitivity, specificity, precision and recovery. Parallelism was demonstrated between the standard curve and serially diluted serum, milk and pituitary derived growth hormone. Sensitivity of the assay was 0.1 ng/ml. Recovery of exogenous bovine somatotropin from serum and milk ranged from 90 to 102% and 96 to 108% respectively. The intra and inter assay variations to measure growth hormone in serum and milk were 3.36 to 8.81% and 6.01 to 12.31% respectively. Statistical analysis for parallelism and cross-reactivity of rbST with serum of other species confirmed the reproducibility of the assay. <br/> <br/>Page(s): 594-598