http://nopr.niscair.res.in/handle/123456789/4404 Search the Channel search http://nopr.niscair.res.in/simple-search http://nopr.niscair.res.in/handle/123456789/4581 Title: Identification of <img src='/image/spc_char/alpha.gif'> amylase inhibitors from <i style="">Syzygium cumini </i>Linn seeds <br/> <br/>Authors: Karthic, K; Kirthiram, K S; Sadasivam, S; Thayumanavan, B; Palvannan, T <br/> <br/>Abstract: <smarttagtype namespaceuri="urn:schemas-microsoft-com:office:smarttags" name="place" downloadurl="http://www.5iantlavalamp.com/"><smarttagtype namespaceuri="urn:schemas-microsoft-com:office:smarttags" name="City" downloadurl="http://www.5iamas-microsoft-com:office:smarttags"> The aqueous extract of <i style="">S. cumini<b style=""> </b></i>or <i style="">Eugenia jambolana</i> seeds<b style=""> </b>and<i> Psidium guajava</i><b style=""> </b>leaves<b style=""> </b>showed higher inhibition against the porcine pancreatic <img src='/image/spc_char/alpha.gif'> -amylase among the medicinal plants studied. The <img src='/image/spc_char/alpha.gif'> -amylase inhibitors from <i>S.cumini</i> seeds were separated from the extract by preparative thin layer chromatography into fractions with different Rf values. The fraction with R<i style="">_f</i> value between 0.285 and 0.43, which showed maximum inhibitory activity, was eluted and analyzed through LC-MS. The compounds identified from the seed extract of <i style="">S. cumini<b style=""> </b></i>were betulinic acid and 3,5,7,4`-tetrahydroxy flavanone, which were reported earlier from <i>S. formosanum</i> and other plants. Dixon plot showed that the inhibition was non-competitive in nature.<i style=""></i> </smarttagtype></smarttagtype> <br/> <br/>Page(s): 677-680 http://nopr.niscair.res.in/handle/123456789/4580 Title: Effect of ⁷Li radiation on endogenous hormonal level on developing cotton fiber <br/> <br/>Authors: Bhatt, Kunjal; Sarma, Asiti; Thaker, Vrinda <br/> <br/>Abstract: <smarttagtype namespaceuri="urn:schemas-microsoft-com:office:smarttags" name="place" downloadurl="http://www.5iantlavalamp.com/"><smarttagtype namespaceuri="urn:schemas-microsoft-com:office:smarttags" name="City" downloadurl="http://www.5iamas-microsoft-com:office:smarttags"> Influence of radiation doses (⁷Li) on cellular metabolism, specially endogenous hormonal level, was studied in monolayer of cotton fibers. Changes in endogenous phytohormone level were determined with two different fluences of ⁷Li equivalent to radiation doses of 1 Gy and 4 Gy. To estimate the endogenous indole-3-acetic acid (IAA), phenoxy acetic acid (PAA), and abscisic acid (ABA) levels, indirect ELISA was performed with the help of antibodies raised against each hormone. In samples at later stage, dose dependent response was apparent in PAA. Results showed that <i>in vivo</i> content of each hormone increased with radiation treatment except ABA. </smarttagtype></smarttagtype> <br/> <br/>Page(s): 673-676 http://nopr.niscair.res.in/handle/123456789/4579 Title: Antimutagenic activity of methanolic extracts of four ayurvedic medicinal plants <br/> <br/>Authors: Aqil, Farrukh; Zahin, Maryam; Ahmad, Iqbal <br/> <br/>Abstract: Methanolic extracts of <i style="">Acorus calamus</i> (Rhizome), <i style="">Hemidesmus indicus</i> (Stem), <i style="">Holarrhena antidysenterica</i> (Bark) and <i style="">Plumbago zeylanica</i> (Root), were tested for their antimutagenic potential. These extracts, at tested concentrations, showed no sign of mutagenicity to <i style="">Salmonella typhimurium</i> tester strains. The extracts of the plants exhibited varying level of antimutagenicity. At a dose of 100 µg/plate, the extracts exhibited the inhibition of His+ revertants from 18.51% to 82.66 % against direct acting mutagens, methyl methanesulphonate (MMS) and sodium azide (NaN₃) induced mutagenicity in <i style="">Salmonella</i> tester strains TA 97a, TA 100, TA 102 and TA 104. However, at lower concentrations (25 and 50 µg/ plate) of the plant extracts, a decrease in antimutagenic activity was recorded. Dose dependent antimutagenic activity of the extracts is also evident from linear regression analysis of the data. The over all antimutagenic potential of above four extracts was found to be in order of <i style="">A. calamus </i>> <i style="">H. indicus</i> > <i style="">H. antidysenterica</i> > <i style="">P. zeylanica</i>. Further, total phenolic content of these extracts did not correlate with its antimutagenic activity in <i style="">A. calamus</i> and <i style="">P. zeylanica</i>. <br/> <br/>Page(s): 668-672 http://nopr.niscair.res.in/handle/123456789/4578 Title: Antidiabetic activity of aqueous extract and non polysaccharide fraction of <i>Cynodon dactylon</i> Pers. <br/> <br/>Authors: Jarald, E E; Joshi, S B; Jain, D C <br/> <br/>Abstract: Petroleum ether (60^o-80^oC), chloroform, acetone, ethanol, aqueous and crude hot water extracts of the whole plant of <i>C</i>.<i> dactylon</i> and the two fractions of aqueous extract were tested for antihyperglycaemic activity in glucose overloaded hyperglycemic rats and in alloxan induced diabetic model at two-dose levels, 200 and 400 mg/kg (po) respectively. The aqueous extract of <i>C. dactylon</i> and the non polysaccharide fraction of aqueous extract were found to exhibit significant antihyperglycaemic activity and only the non polysaccharide fraction was found to produce hypoglycemia in fasted normal rats. Treatment of diabetic rats with aqueous extract and non polysaccharide fraction of the plant decreased the elevated biochemical parameters, glucose, urea, creatinine, serum cholesterol, serum triglyceride, high density lipoprotein, low density lipoprotein, haemoglobin and glycosylated haemoglobin significantly. Comparatively, the non polysaccharide fraction of aqueous extract was found to be more effective than the aqueous extract. <br/> <br/>Page(s): 660-667