http://nopr.niscair.res.in/handle/123456789/3864 Search the Channel search http://nopr.niscair.res.in/simple-search http://nopr.niscair.res.in/handle/123456789/3878 Title: Mild and efficient synthesis of 1,2,4-triazolo[4,3-⍺][1,8] naphthyridines using FeCl₃ in the solid state <br/> <br/>Authors: Mogilaiah, K; Vidya, K; Swamy, T Kumara <br/> <br/>Abstract: An efficient, rapid and mild method for the synthesis of 1,2,4-triazolo-[4,3-⍺][1,8]naphthyridines <b>4</b> by the oxidative cyclization of vanillin 3-aryl-1,8-naphthyridine-2-yl hydrazones <b>3</b> with FeCl₃.6H₂O in the solid state by grinding at room temperature has been described. The products are obtained in good yields with high purity. <br/> <br/>Page(s): 599-601 http://nopr.niscair.res.in/handle/123456789/3877 Title: The synthesis and structure of 1-[3-{(2-hydroxybenzylidene)amino}phenyl]ethanone <br/> <br/>Authors: De, Rajib Lal; Mukherjee, Jaydeep; Mandal, Mahuya; Roy, Lovely; Bhowal, Ruchika; Banerjee, Indrajit <br/> <br/>Abstract: Two Schiff base ligands SACPN<i style="">y</i>H <b>1</b> and 5BrSACPN<i style="">y</i>H <b>2</b> are synthesized from the condensation reactions of salicylaldehyde and 5-bromosalicylaldehyde respectively with 3-amino­aceto­phenone and characterized by elemental analyses, mass, electronic, infrared spectral studies. The molecular structure of <b>1</b> is determined by the single crystal X-ray crystallographic study. <span style="color: rgb(51, 51, 51);" lang="EN-GB">Space group,monoclinic, P2₁/n; Z = 4; a = 14.8717(11)<span style="color: rgb(51, 51, 51);" lang="EN-GB">Å<span style="color: rgb(51, 51, 51);" lang="EN-GB">, b = 5.4559(4) <span style="color: rgb(51, 51, 51);" lang="EN-GB">Å<span style="color: rgb(51, 51, 51);" lang="EN-GB">, c = 16.7192(12) Ǻ, β = 115.959(3)^o. </span></span></span></span></span> <br/> <br/>Page(s): 595-598 http://nopr.niscair.res.in/handle/123456789/3876 Title: <i style="">N</i>-Desmethyltriptans: One pot efficient synthesis of <i>N</i>-methyl-2-[5-[substituted-1<i>H</i>-indole-3-yl]ethanamines<i style=""> </i> <br/> <br/>Authors: Mittapelli, Vasantha; Ray, Purna Chandra; Chauhan, Yogendra Kumar; Datta, Debashish <br/> <br/>Abstract: A straightforward and highly improved method to synthesize N-methyl-2-[5-[substituted-1H-indole-3-yl]ethanamines <b style="">4-6</b>, which are the metabolites of tryptans <b>1-3</b>, is reported<b>. </b>The significance of the process is its simplicity and efficiency in isolating the N-desmethyltriptans derivatives as a free base. <br/> <br/>Page(s): 590-594 http://nopr.niscair.res.in/handle/123456789/3875 Title: Conformational analysis of some <i>N</i>-hydroxypiperidin-4-one oximes <br/> <br/>Authors: Baskar, G; Gopalakrishnan, M; Jabaraj, J Winfred <br/> <br/>Abstract: Analysis of the spectral data (¹H NMR and¹³C NMR) indicates that out of ten <i>N</i>-hydroxypiperidin-4-one oximes <b>3a-j</b>, the compounds <b>3b</b> and <b>3c</b> exist predominantly in chair conformation with the aryl and alkyl substituents in the equatorial positions, whereas the compounds <b>3d-j</b> exist in boat conformation. The introduction of an oxime group at C-4 causes a flattening of the ring about C(5)-C(6) bond. The NOESY spectrum (Nuclear Overhauser effect) recorded for the compound <b>3d</b> further supports the assigned boat conformation. <br/> <br/>Page(s): 580-584