http://nopr.niscair.res.in/handle/123456789/319 Search the Channel search http://nopr.niscair.res.in/simple-search http://nopr.niscair.res.in/handle/123456789/756 Title: Al₂O₃ catalyzed Friedlander synthesis of 1, 8-naphthyridines in the solid state <br/> <br/>Authors: Mogilaiah, K; Vidya, K <br/> <br/>Abstract: Al₂O₃ catalyzes efficiently the Freidlander condensation of 2-aminonicotinaldehyde 1 with various carbonyl compounds containing ⍺-methylene group 2 in the solid state to afford the corresponding 1,8-naphthyridines 3. The reaction proceeds efficiently at room temperature in good yields and in a state of high purity. <br/> <br/>Page(s): 1721-1723 http://nopr.niscair.res.in/handle/123456789/754 Title: Clay-catalyzed high-speed synthesis of thiadiazepine in one-pot <br/> <br/>Authors: Siddiqui, Ibadur R; Singh, Pravin K; Srivastava, Vishal; Singh, J <br/> <br/>Abstract: Microwave assisted clay-catalyzed solid state integrated chemical process which enables the consumption of toxic inter-mediates and their isolation from environment, reduce reaction time, cost and complex isolation procedures enhances yields are effective for realizing a green chemical process in library synthe-ses of bio-active compounds. This is described here in the synthe-sis of thiadiazepine. Antifungal screening results on Fusarium oxysporum and Penicillium citrinum show that most of the syn-thesized compounds display promising antifungal activity, compa-rable with griseofulvin and dithane M-45 as standards. <br/> <br/>Page(s): 1716-1720 http://nopr.niscair.res.in/handle/123456789/752 Title: Dehydroacetic acid and its derivatives in organic synthesis: Synthesis of some new 2-substituted-4- (5-bromo-4-hydroxy-6-methyl- 2H-pyran-2-one-3-yl)thiazoles <br/> <br/>Authors: Prakash, Richa Prakash; Kumar, Ajay; Singh, Shiv P <br/> <br/>Abstract: Synthesis of 3 β,3β,5-tribromoacetyl-4-hydroxy-6- methyl-2H-pyran-2-one 2 from the bromination of DHA 1 in chloroform has been reported. The reaction of 2 with various thioureas/thioamides leads to an efficient synthesis of new 2-substituted-4-(5-bromo-4-hydroxy-6-methyl- 2H-pyran-2-one-3-yl)thiazoles. <br/> <br/>Page(s): 1713-1715 http://nopr.niscair.res.in/handle/123456789/751 Title: Synthesis and studies of some novel s-triazine based aminopyrimidines, isoxazoles and 1,5-benzothiazepines <br/> <br/>Authors: Solankee, Anjani; Kapadia, Kishor; Solankee, Pankit; Prajapati, Yogesh; Patel, Hiral; Solankee, Sejal <br/> <br/>Abstract: An elegant synthesis of the titled compounds 7a-e, 8a-e and 9a-e have been presented starting from chalcones 6a-e based on s-triazine nucleus. These chalcones 6a-e on cyclisation with guanidine nitrate and hydroxylamine hydrochloride in the presence of alkali give aminopyrimidines 7a-e and isoxazoles 8a-e respectively. Further these chalcones 6a-e on cyclisation with 2-aminothiophenol in the presence of few drops of glacial acetic acid give 1,5-benzothiazepines 9a-e. All the products obtained from these reactions are characterized by elemental analysis, IR, ¹H NMR and mass spectral data. <br/> <br/>Page(s): 1707-1712