http://nopr.niscair.res.in/handle/123456789/13090 Search the Channel search http://nopr.niscair.res.in/simple-search http://nopr.niscair.res.in/handle/123456789/13119 Title: Physicochemical parametric analysis of paper mill effluent using mixed cultures of bacteria and fungi <br/> <br/>Authors: Saraswathi, R; Saseetharan, M K <br/> <br/>Abstract: This study used shake flask method to examine effects of pH, temperature, and duration of incubation on removal efficiency by studying physicochemical parameters and floc stability in degradation of pulp and paper mill effluent over 24 h using mixed cultures of bacteria and fungi. A 2⁴ full factorial central composite design and response surface methodology were adopted to plan experiments and analyze the data, respectively. Quadratic models were developed based on high coefficient of determination (R²) obtained from analysis of variance (ANOVA) results. Optimal conditions yielded a decrease in chemical oxygen demand (COD,70%) and in total suspended solid (TSS, 53%) levels. <br/> <br/>Page(s): 1070-1078 http://nopr.niscair.res.in/handle/123456789/13118 Title: Energy optimization in integrated pulp and paper mills with recourse to environmental benefits <br/> <br/>Authors: Pharande, V A; Asthana, S R; Saini, D R; Kaul, S N <br/> <br/>Abstract: This study focuses on energy optimization in evaporator and digester of integrated pulp and paper mills in India, and recommends application of 7 effects/plates evaporator in place of 5 effects/plates normally used. Steam economy resulting from this modification is definitely more than 7. Pinch technology is found suitable for optimization of controlled parameters in the digester. Using recommendations, total energy savings was observed in West Coast Paper Mill (11.74%) and Star Paper Mill (12.97%). Environmental benefits that will accrue in terms of reductions in emissions are: SPM, 46464-48664 TPA; SO₂ , 1045 kg/annum; H₂S, 55,020 kg/annum; and CO₂, 13612 TPA. <br/> <br/>Page(s): 1061-1069 http://nopr.niscair.res.in/handle/123456789/13117 Title: Preparation of novel catalyst composition from natural waste for biodiesel production <br/> <br/>Authors: Semwal, Surbhi; Arora, Ajay K; Prakash, Shanti; Puri, Suresh K; Tuli, Deepak K <br/> <br/>Abstract: This study presents preparation of a novel, cost effective and recyclable catalyst from natural waste for production of biodiesel. Novel catalyst composition has been developed using combination of seashell and eggshell in complexation with transition metal oxide TiO2 to form A-B-O type metal oxide complex, where A is alkaline metal and B is transition metal. Catalyst composition has been evaluated and a robust cost effective method for biodiesel production is proposed. <br/> <br/>Page(s): 1054-1060 http://nopr.niscair.res.in/handle/123456789/13116 Title: Evaluation of PEGylation reaction and purification of monoPEGylated recombinant human granulocyte colony stimulating factor <br/> <br/>Authors: Tiwari, Krishnanand; Kattavarapu, Krishna; Shebannavar, Sunil N; Pokalwar, Santosh.; Mishra, Maheshwari K; Chauhan, Ugam Kumari S <br/> <br/>Abstract: In this study, incubation of methoxy polyethylene glycol propionaldehyde (mPEG-ALD) with recombinant human granulocyte colony stimulating factor (rh-GCSF) in presence of  cyanoborohydride yielded various species of polyethylene glycol (PEG) conjugated GCSF as detected by size exclusion high performance liquid chromatography (SE-HPLC). These reactions were carried out at 1:5 molar ratio of rh-GCSF to PEG at 20-25°C. At 1 h of reaction, mainly monoPEGylated GCSF (62.4%) was formed. At 2 h of reaction, multi PEGylated GCSF (conc. 9%) was detected, where monoPEGylated GCSF constituted the most (73.2%). At 3 h of reaction, monoPEGylated (76.2%) and multi PEGylated GCSF (11.3%) were formed. Further, a process involving ion exchange and gel filtration chromatography were used to obtain pure monoPEGylated GCSF. Purified monoPEGylated GCSF was comparable to standard PEGylated rh-GCSF on NFS-60 cell line, suggesting retained biological activity of monoPEGylated GCSF. Further, the procedure is warranted for purification of other monoPEGylated proteins for therapeutic purpose. <br/> <br/>Page(s): 1049-1053